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CYP24 / CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

CYP24 / CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: cytochrome P450, family 24, subfamily A, polypeptide 1
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP24A1, 24-OHase, CP24, CYP24, Cytochrome P450-CC24, Exo-mitochondrial protein, HCAI, p450-CC24, Vitamin D 24-hydroxylase, Cytochrome P450 24A1, Vitamin D(3) 24-hydroxylase
Target Sequences: NM_000782 NP_000773.2 Q07973

Publications (1)

1
Hemoglobin alters vitamin carrier uptake and vitamin D metabolism in proximal tubule cells: implications for sickle cell disease. Megan L Gliozzi, Youssef Rbaibi, Kimberly R Long, Dario A Vitturi, Ora A Weisz. American journal of physiology. Cell physiology. 2019 November;317:C993-C1000. [Full Text Article] [PubMed:31509446] [PMC:PMC6879883] Related Antibodies: LS-C407760.

☰ Filters
Antibodies (41)
ELISA Kits (10)
Proteins (3)
Cell-Based (1)
Primary (41)
Recombinant (3)
Sandwich (8)
Sandwich CLIA (1)
CYP24 / CYP24A1 (54)
Human (38)
Mouse (19)
Rat (5)
Bovine (3)
Chicken (1)
Chimpanzee (3)
Dog (6)
Gibbon (3)
Monkey (5)
Pig (6)
Porcine (1)
Rabbit (4)
Sheep (1)
IHC (9)
IHC-P (6)
WB (40)
ELISA (3)
IF (1)
Peptide-ELISA (6)
rabbit (39)
mouse (1)
goat (1)
Product Group
IHCPlus (2)
IgG (9)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (40)
1E1 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (7)
APC (2)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (21)
aa260-514 (8)
aa37-250 (8)
aa263-312 (4)
aa420-469 (4)
aa153-514 (2)
380-460 aa, C-terminal (1)
C-Terminus (1)
aa34-64 (1)
aa390-439 (1)
aa400-450 (1)
aa411-460 (1)
aa466-494 (1)
aa480-514 (1)
aa481-490 (1)
No (53)
Yes (1)
Adherent Cell Cultures (1)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
GST, N-terminus (1)
His-T7 (2)
Human (2)
Mouse (1)
E. coli (2)
Wheat Germ Extract (1)
CYP24 / CYP24A1 Antibody - CYP24A1 antibody IHC-paraffin. IHC(P): Rat Kidney Tissue.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa153-514) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CYP24 / CYP24A1 Antibody - Anti-CYP24 / CYP24A1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CYP24 / CYP24A1 Goat anti-Human Polyclonal (aa481-490) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CYP24 / CYP24A1 Antibody - Immunohistochemistry of paraffin-embedded rat lung using CYP24A1 antibodyat dilution of 1:200 (40x lens).
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CYP24 / CYP24A1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa400-450) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CYP24 / CYP24A1 ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CYP24 / CYP24A1 Antibody
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa153-514) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
CYP24 / CYP24A1 Antibody - Western blot of CYP24A1 antibody
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (380-460 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP24 / CYP24A1 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP24 / CYP24A1 Antibody - Formalin-fixed and paraffin-embedded human spleen tissue reacted with CYP24A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa466-494) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CYP24 / CYP24A1 Antibody - Immunohistochemical analysis of Cytochrome P450 24A1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CYP24 / CYP24A1 Antibody - Western Blot analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M02), clone 1E1.Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa).Lane 2: Non-transfected lysate.
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CYP24 / CYP24A1 Mouse anti-Human Monoclonal (1E1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CYP24 / CYP24A1 Antibody - Western blot analysis of extracts from HUVEC cells, using Cytochrome P450 24A1 antibody.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CYP24 / CYP24A1 Antibody - Western blot analysis of lysates from JurKat cells, using Cytochrome P450 24A1 Antibody. The lane on the right is blocked with the synthesized peptide.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa411-460) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CYP24 / CYP24A1 Antibody - Western blot analysis of the lysates from HepG2 cells using Cytochrome P450 24A1 antibody.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa390-439) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CYP24 / CYP24A1 Antibody - All lanes : Anti-CYP24A1 Antibody at 1:2000 dilution Lane 1: A431 whole cell lysates Lane 2: HeLa whole cell lysates Lane 3: HepG2 whole cell lysates Lane 4: MOLT-4 whole cell lysates Lane 5: Raji whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa34-64) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
CYP24 / CYP24A1 Antibody - Anti-CYP24A1 Antibody at 1:2000 dilution + HepG2 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa480-514) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
CYP24 / CYP24A1 Antibody - Western blot of recombinant CYP24 / CYP24A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Mouse Polyclonal (aa260-514) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CYP24 / CYP24A1 Antibody - Western blot of recombinant CYP24 / CYP24A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Mouse Polyclonal (aa260-514) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CYP24 / CYP24A1 Antibody - Western blot of recombinant CYP24 / CYP24A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Mouse Polyclonal (aa260-514) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
CYP24 / CYP24A1 Antibody - Western blot of recombinant CYP24 / CYP24A1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Mouse Polyclonal (aa260-514) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CYP24 / CYP24A1 Antibody - CYP24A1 / CYP24 antibody Western blot of Placenta lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa420-469) Antibody
Human
WB
Unconjugated
100 µl/$424
CYP24 / CYP24A1 Antibody - CYP24A1 / CYP24 antibody Western blot of MDA-MB-435S cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa263-312) Antibody
Human
WB
Unconjugated
100 µl/$424
CYP24 / CYP24A1 Antibody - Western blot of CYP24 / CYP24A1 antibody.
Select
CYP24 / CYP24A1 Rabbit anti-Human Polyclonal (aa37-250) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Select
CYP24 / CYP24A1 Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$331
Viewing 1-25 of 54 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).