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CYP11B2 / Aldosterone Synthase

cytochrome P450, family 11, subfamily B, polypeptide 2

CYP11B2 / Aldosterone Synthase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Gene Name: cytochrome P450, family 11, subfamily B, polypeptide 2
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP11B2, ALDOS, Aldosterone synthase, CYP11BL, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, P-450C18, p450aldo, Steroid 18-hydroxylase, Steroid 11-beta-monooxygenase, CYP11B, p450C18, Steroid 11-beta/18-hydroxylase
Target Sequences: NM_000498 NP_000489.3 P19099

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CYP11B2 / Aldosterone Synthase (4)
No (4)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Yeast (1)
Purified (2)
CYP11B2 / Aldosterone Synthase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CYP11B2 / Aldosterone Synthase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
CYP11B2 / Aldosterone Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
57.56 kDa
20 µg/$215
CYP11B2 / Aldosterone Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
57.56 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).