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CYCS / Cytochrome c

cytochrome c, somatic

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Gene Name: cytochrome c, somatic
Synonyms: CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic
Target Sequences: NM_018947 NP_061820.1 P99999

Publications (3)

1
Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease. She P, Zhang Z, Marchionini D, Diaz WC, Jetton TJ, Kimball SR, Vary TC, Lang CH, Lynch CJ. American journal of physiology. Endocrinology and metabolism. 2011 301:E49-61. [PubMed:21505144] [PMC:PMC3129844] Related Antibodies: LS-C41042.
2
Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species. McGuire KA, Barlan AU, Griffin TM, Wiethoff CM. Journal of virology. 2011 85:10806-13. [PubMed:21835790] [PMC:PMC3187480] Related Antibodies: LS-C41042.
3
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Emilie Barruet , Steven M Garcia , Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz. eLife. 2020 Apr;9:e51576. [Full Text Article] [PubMed:32234209] [PMC:PMC7164960]

☰ Filters
Products
Antibodies (138)
Primary (138)
CYCS / Cytochrome c (138)
Human (119)
Mouse (90)
Rat (103)
Bovine (7)
Chicken (4)
Chimpanzee (3)
Dog (13)
Drosophila (16)
E. coli (5)
Frog (6)
Gibbon (3)
Guinea pig (1)
Hamster (7)
Horse (28)
Monkey (5)
Orangutan (3)
Pig (12)
Pigeon (3)
Rabbit (18)
Sheep (5)
Xenopus (3)
IHC (55)
IHC-Fr (5)
IHC-P (29)
WB (116)
Flo (27)
ELISA (35)
ICC (7)
ID (3)
IE (3)
IF (34)
IP (15)
Neut (1)
Peptide-ELISA (3)
rabbit (70)
mouse (64)
sheep (4)
Product Group
IHCPlus (5)
IgG (41)
IgG1 (15)
IgG1,k (5)
IgG1b,k (6)
IgG2a (2)
IgG2a,k (8)
IgG2b (3)
IgG2b,k (19)
monoclonal mc (64)
polyclonal pc (74)
15F10 (1)
2G8 (1)
4B10 (1)
6H2 (1)
6H2.B4 (5)
7H8.2C12 (9)
7H8.2C12 + CYCS/1010 (3)
8G3 (1)
ABM30D4 (1)
CTC05 (3)
CYCS/1010 (3)
OTI2F2 (2)
SPM389 (2)
APC (3)
APC Conjugated (6)
Azide-free (6)
Biotin Conjugated (13)
BSA-free (6)
Carrier-free (1)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (9)
HRP Conjugated (9)
Magnetic beads Conjugated (1)
PE Conjugated (7)
Preservative Free (1)
Ready-to-Use (4)
Sepharose Conjugated (1)
Unconjugated (84)
aa13-99 (9)
aa1-80 (8)
aa5-100 (8)
aa10-59 (5)
aa91-105 (4)
aa2-105 (2)
aa66-104 (2)
C-Terminus (1)
His19 (1)
N-Terminus (1)
aa1-188 (1)
aa1-80, aa81-104, aa66-104 (1)
aa21-55 (1)
aa55-105 (1)
No (137)
Yes (1)
CYCS / Cytochrome c Antibody - Anti-Cytochrome c antibody IHC of human bone marrow. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CYCS / Cytochrome c Mouse anti-Pigeon Monoclonal (aa1-80) (7H8.2C12) Antibody
Pigeon, Drosophila, Horse, Mouse, Rat, Hamster, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CYCS / Cytochrome c Antibody - Anti-Cytochrome c antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CYCS / Cytochrome c Mouse anti-Horse Monoclonal (7H8.2C12) Antibody
Mouse, Rat, Horse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CYCS / Cytochrome c Antibody - Cytochrome c was immunoprecipitated from Hela cell extract (1% NP-40) using 2-4 ug 6H2. B4 antibody/1 x107 cell equivalents. Immunoprecipitates were resolved by electrophoresis, transferred to nitrocellulose, and probed with the 7H8.2C12 anti-cytochrome c antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. In addition to the specific 15 kD cytochrome c band immunoprecipitated by 6H2. B4, heavy and light immunoglobulin chains are recognized by the goat anti-mouse secondary antibody.
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CYCS / Cytochrome c Mouse anti-Mouse Monoclonal (6H2.B4) Antibody
Mouse, Rat, Human
Flo, IF, IP, WB
Unconjugated
25 µg/$264; 100 µg/$342
CYCS / Cytochrome c Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CYCS / Cytochrome c Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$460
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CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
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CYCS / Cytochrome c Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, IF, IP
Unconjugated
100 µg/$801
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CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, ID, IE, WB
Unconjugated
5 mg/$558
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CYCS / Cytochrome c Sheep anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human
IF, IP, WB
Unconjugated
100 µg/$842
CYCS / Cytochrome c Antibody - Immunohistochemical analysis of Cytochrome c staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CYCS / Cytochrome c Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (CYCS/1010).
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (CYCS/1010).
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Antibody - IHC analysis of Cytochrome C using anti-Cytochrome C antibody. Cytochrome C was detected in paraffin-embedded section of human lung cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-Cytochrome C antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (15F10) Antibody
Mouse, Rat, Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human salivary tumor stained with Cytochrome C antibody (7H8.2C12).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human salivary tumor stained with Cytochrome C antibody (7H8.2C12).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Azide-free, BSA-free) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (CTC05).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (CTC05).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (CTC05).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Human Monoclonal (Ready-to-Use) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
CYCS / Cytochrome c Antibody - Cytochrome C antibody IHC-paraffin: Mouse Brain Tissue.
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CYCS / Cytochrome c Rabbit anti-Human Polyclonal (aa2-105) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CYCS / Cytochrome c Antibody - IHC-P: Cytochrome C antibody testing of human intestinal cancer tissue
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CYCS / Cytochrome c Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$575
CYCS / Cytochrome c Antibody - Cytochrome c antibody for IHC in human colorectal tissue
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CYCS / Cytochrome c Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (7H8.2C12 + CYCS/1010).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (7H8.2C12 + CYCS/1010) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (7H8.2C12 + CYCS/1010).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Ready-to-Use) (7H8.2C12 + CYCS/1010) Antibody
Rat, Pig, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human heart stained with Cytochrome C antibody (7H8.2C12 + CYCS/1010).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Azide-free, BSA-free) (7H8.2C12 + CYCS/1010) Antibody
Rat, Pig, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human salivary tumor stained with Cytochrome C antibody (SPM389).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa66-104) (SPM389) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
CYCS / Cytochrome c Antibody - Formalin-fixed, paraffin-embedded human salivary tumor stained with Cytochrome C antibody (SPM389).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa66-104) (Azide-free, BSA-free) (SPM389) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).