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Unfortunately, the antibody (ID:90028) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



CXCR4

chemokine (C-X-C motif) receptor 4

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Gene Name: chemokine (C-X-C motif) receptor 4
Family/Subfamily: GPCR , Chemokine
Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR
Target Sequences: NM_003467 NP_003458.1 P61073

Publications (5)

1
Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX. The Journal of biological chemistry. 2007 282:9547-55. [PubMed:17289675] [PMC:PMC2366813] Related Antibodies: LS-B1986.
2
VEGFR1/ CXCR4 positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1 dependent mechanism. Andrew Wragg, Jason A Mellad, Leilani E Beltran, Mikhail Konoplyannikov, Hong San, Sherry Boozer, Robert J. Deans, Anthony Mathur, Robert J Lederman, Jason C Kovacic, and Manfred Boehm. Journal of molecular medicine (Berlin, Germany). 2008 86:1221-32. (Flo; Rat) [Full Text Article] [PubMed:18690419] [PMC:PMC2575081]
3
Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Isnardi I, Ng YS, Menard L, Meyers G, Saadoun D, Srdanovic I, Samuels J, Berman J, Buckner JH, Cunningham-Rundles C, Meffre E. Blood. 2010 115:5026-36. [PubMed:20231422] [PMC:PMC3373152] Related Antibodies: LS-B1986.
4
Cellular and subcellular localization of CXCL12 and CXCR4 in rat nociceptive structures: physiological relevance. Reaux-Le Goazigo A, Rivat C, Kitabgi P, Pohl M, Melik Parsadaniantz S. The European journal of neuroscience. 2012 Sep;36:2619-31. [Full Text Article] [PubMed:22694179] Related Antibodies: LS-A1380.
5
CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2. Ghosh MC, Makena PS, Gorantla V, Sinclair SE, Waters CM. American journal of physiology. Lung cellular and molecular physiology. 2012 May;302:L846-56. [Full Text Article] [PubMed:22345572] [PMC:PMC3362158] Related Antibodies: LS-C250.
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Filtered By: None
Target
cxcr4 (123)
Reactivity
Human (111)
Mouse (49)
Rat (32)
Baboon (1)
Bat (3)
Bovine (7)
Cat (1)
Chicken (1)
Chimpanzee (3)
Dog (7)
Hamster (4)
Horse (3)
Monkey (18)
Pig (5)
Rabbit (8)
Sheep (4)
Xenopus (5)
Zebrafish (1)
Application
IHC (34)
IHC-Fr (2)
IHC-P (26)
WB (98)
Flo (25)
ELISA (38)
Func (1)
ICC (6)
IF (13)
IP (12)
Host
rabbit (92)
mouse (11)
goat (16)
rat (4)
Isotype
IgG (71)
IgG1 (3)
IgG2a (10)
IgG2b (2)
Clonality
monoclonal mc (16)
polyclonal pc (107)
Clone
12G5 (3)
247506 (1)
A145 (2)
Format
AP Conjugated (8)
APC Conjugated (4)
Azide-free (3)
Biotin Conjugated (11)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (11)
HRP Conjugated (10)
Magnetic beads Conjugated (1)
PE Conjugated (10)
PerCP Conjugated (1)
Sepharose Conjugated (1)
Unconjugated (63)
Epitope
N-Terminus (14)
aa50-79 (5)
pSer339 (4)
2nd Extracellular Domain (3)
C-Terminus (3)
aa14-40 (3)
Cytoplasmic Domain (2)
aa1-14 (2)
aa18-33 (2)
aa328-338 (2)
Val340 (1)
aa1-359 (1)
aa17-42 (1)
aa17-43 (1)
aa182-196 (1)
aa184-193 (1)
aa2-38 (1)
aa270-350 (1)
aa28-63 (1)
aa300-349 (1)
aa31-43 (1)
aa54-83 (1)
Publications
No (120)
Yes (3)
Showing 1-25 out of 123 results
Anti-CXCR4 Antibody (Cytoplasmic Domain) IHC-plus™ LS-A1380

Rabbit Polyclonal to Human CXCR4
Chicken, Rabbit, Mouse, Rat, Hamster, Human, Monkey
IHC-P
Unconjugated
Anti-CXCR4 Antibody (clone 12G5) IHC-plus™ LS-B1986

Mouse Monoclonal [clone 12G5] (IgG2a) to Human CXCR4
Human, Monkey, Baboon
Flo IF IHC-Fr IHC-P
Unconjugated
Anti-CXCR4 Antibody (aa14-40) IHC-plus™ LS-B2484

Goat Polyclonal (IgG) to Mouse CXCR4
Mouse, Human
ELISA ICC IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (N-Terminus) IHC-plus™ LS-A1376

Rabbit Polyclonal to Human CXCR4
Human
IHC-P
Unconjugated
Anti-CXCR4 Antibody (aa14-40) IHC-plus™ LS-B3306

Goat Polyclonal to Mouse CXCR4
Mouse, Human
ELISA IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa182-196) IHC-plus™ LS-B2160

Rabbit Polyclonal to Human CXCR4
Mouse, Human
IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa300-349) IHC-plus™ LS-B6709

Rabbit Polyclonal (IgG) to Human CXCR4
Mouse, Rat, Human
ELISA IF IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (C-Terminus) IHC-plus™ LS-A1381

Rabbit Polyclonal to Human CXCR4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC-P
Unconjugated
Anti-CXCR4 Antibody (C-Terminus) LS-C37615

Rabbit Polyclonal (IgG) to Human CXCR4
Human
ELISA WB
Unconjugated
Anti-CXCR4 Antibody (N-Terminus) LS-C250

Rabbit Polyclonal to Human CXCR4
Mouse, Human
ICC IP WB
Unconjugated
Anti-CXCR4 Antibody (clone 247506, PE) LS-C36050

Rat Monoclonal [clone 247506] (IgG2b) to Mouse CXCR4
Mouse
Flo
PE Conjugated
Anti-CXCR4 Antibody (aa328-338) LS-C663

Rabbit Polyclonal (IgG) to Human CXCR4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
Anti-CXCR4 Antibody (clone A145, FITC) LS-C179379

Rat Monoclonal [clone A145] (IgG1)
Human
Flo
FITC Conjugated
Anti-CXCR4 Antibody (Cytoplasmic Domain) IHC-plus™ LS-A1377

Rabbit Polyclonal to Human CXCR4
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC-P
Unconjugated
Anti-CXCR4 Antibody (aa18-33) LS-C121684

Rabbit Polyclonal to Human CXCR4
Dog, Sheep, Bovine, Human
IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa184-193) LS-C87223

Goat Polyclonal to Zebrafish CXCR4
Zebrafish
ELISA
Unconjugated
Anti-CXCR4 Antibody LS-C369499

Rabbit Polyclonal (IgG) to Human CXCR4
Human
ELISA IHC WB
Unconjugated
Anti-CXCR4 Antibody LS-C179965

Rabbit Polyclonal to Human CXCR4
Mouse, Rat, Human
ICC IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa14-40) LS-C187703

Goat Polyclonal (IgG) to Mouse CXCR4
Mouse
ELISA IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (N-Terminus) IHC-plus™ LS-B6858

Rabbit Polyclonal (IgG) to Human CXCR4
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (2nd Extracellular Domain) LS-C6303

Rabbit Polyclonal (IgG) to Human CXCR4
Mouse, Human, Monkey
Flo WB
Unconjugated
Anti-CXCR4 Antibody (2nd Extracellular Domain) LS-C88690

Rabbit Polyclonal (IgG) to Human CXCR4
Mouse, Human, Monkey
Flo WB
Unconjugated
Anti-CXCR4 Antibody (aa17-42) LS-C83944

Goat Polyclonal to Human CXCR4
Human
ELISA IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa17-43) LS-C187839

Goat Polyclonal (IgG) to Human CXCR4
Human
ELISA IHC-P WB
Unconjugated
Anti-CXCR4 Antibody (aa1-14) LS-C14373

Rabbit Polyclonal (IgG) to Human CXCR4
Human
IHC-Fr IP WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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