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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
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866-206-6909 (Toll Free North America)
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CXCR3

chemokine (C-X-C motif) receptor 3

CXCR3 is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene Name: chemokine (C-X-C motif) receptor 3
Family/Subfamily: GPCR , Chemokine
Synonyms: CXCR3, C-x-c chemokine receptor 3, CD183 antigen, CKR-L2, CXCR-3, CMKAR3, CD182, CD183, Cxcr3a, GPR9, IP-10 receptor, IP10-R, Mig receptor, MigR, Mig-R, Chemokine (C-X-C) receptor 3, CXC-R3, Cxcr3b, G protein-coupled receptor 9, IP10 receptor
Target Sequences: NM_001504 NP_001495.1 P49682

Publications (3)

1
Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. Denkert C, Loibl S, Noske A, Roller M, Mller BM, Komor M, Budczies J, Darb-Esfahani S, Kronenwett R, Hanusch C, von Trne C, Weichert W, Engels K, Solbach C, Schrader I, Dietel M, von Minckwitz G. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010 28:105-13. (IHC-P; Human) [PubMed:19917869] Related Antibodies: LS-C6283.
2
Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Mikucki ME, Fisher DT, Matsuzaki J, Skitzki JJ, Gaulin NB, Muhitch JB, Ku AW, Frelinger JG, Odunsi K, Gajewski TF, Luster AD, Evans SS. Nature communications. 2015 6:7458. (Block; Human) [Full Text Article] [PubMed:26109379] [PMC:PMC4605273] Related Antibodies: LS-C6283.
3
CXCR3 regulates CD4+ T cell cardiotropism in pressure overload-induced cardiac dysfunction. Ngwenyama N, Salvador AM, Velázquez F, Nevers T, Levy A, Aronovitz M, Luster AD, Huggins GS, Alcaide P. JCI insight. 2019 April;4:pii: 125527. [Full Text Article] [PubMed:30779709] [PMC:PMC6483643] Related Antibodies: LS-B10183.

Viewing 1-25 of 70 items
CXCR3 Antibody - Anti-CXCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
Rabbit Polyclonal to Human CXCR3
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CXCR3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
Rabbit Polyclonal to Human CXCR3
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
CXCR3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
Rabbit Polyclonal to Human CXCR3
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
CXCR3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human CXCR3
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
CXCR3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
Rabbit Polyclonal to Human CXCR3
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
CXCR3 Antibody - Anti-CXCR3 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
(1) Publication(s)
Rabbit Polyclonal (IgG) to Human CXCR3
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
Select
(2) Publication(s)
Mouse Monoclonal [clone 2AR1] (IgG1) to Human CXCR3
Human
Flo, Func, IHC, Neut
Unconjugated
100µg   $710.00
Select
Mouse Monoclonal [clone 2AR1] (IgG1) to Human CXCR3
Human
Flo
CF Conjugated
1ml   $575.00
CXCR3 Antibody - Anti-CXCR3 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human CXCR3
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
CXCR3 Antibody - Immunohistochemistry of paraffin-embedded human stomach cancer tissue using CXCR3 antibody.
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Rabbit Polyclonal (IgG) to Human CXCR3
Mouse, Human
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
CXCR3 Antibody - Western blot of CXCR3 in human pancreas cell lysate using CXCR3 Antibody at 2 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
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Rabbit Polyclonal to Human CXCR3
Mouse, Human
WB
Unconjugated
100µg   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
CXCR3 Antibody - Goat Anti-CXCR3 / GPR9 Antibody Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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Goat Polyclonal to Human CXCR3
Human, Monkey
IF, Peptide-ELISA
Unconjugated
100µg   0.5mg/ml   $335.00
CXCR3 Antibody - Immunohistochemistry Dilution at 1:1200 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   0.42mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human CXCR3
Human
WB
Unconjugated
100µg   $530.00
Select
Mouse Monoclonal [clone 5C10B3] (IgG1) to Human CXCR3
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl   $365.00
Select
Mouse Monoclonal [clone 5C10E6] (IgG1) to Human CXCR3
Human
ELISA, Flo, IHC, WB
Unconjugated
100µl   $365.00
CXCR3 Antibody - CXCR3 antibody IHC-paraffin: Rat Kidney Tissue.
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Rabbit Polyclonal to Human CXCR3
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $325.00

Viewing 1-25 of 70 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).