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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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CXCR1

chemokine (C-X-C motif) receptor 1

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Gene Name: chemokine (C-X-C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: CXCR1, C-C, Chemokine c-x-c receptor 1, CKR-1, CMKAR1, CD128, CD181, CD181 antigen, CXCR-1, CXC-R1, IL-8R A, Il8 receptor a, Interleukin 8 receptor a, Interleukin 8 receptor alpha, Interleukin 8 receptor, alpha, Interleukin-8 receptor type A, IL8RBA, Interleukin-8 receptor type 1, C-C-CKR-1, CDw128a, IL-8 receptor type 1, IL8R1, IL8RA
Target Sequences: NM_000634 NP_000625.1 P25024

Publications (2)

1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C178869.
2
ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Wilson BJ, Saab KR, Ma J, Schatton T, P[Character fc]tz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH. Cancer research. Aug;74:4196-207. [Full Text Article] [PubMed:24934811] [PMC:PMC4119553] Related Antibodies: LS-A806.

Viewing 1-25 of 32 items
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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(1) Publication(s)
Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
FITC Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
AP Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
APC Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human CXCR1
Human
ICC, IHC, IHC-P
PE Conjugated
100µl   $650.00
CXCR1 Antibody - Human Liver, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CXCR1 Antibody
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(1) Publication(s)
Rabbit Polyclonal to Human CXCR1
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $255.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
CXCR1 Antibody - CXCR1 antibody. IHC(P): Human Lung Cancer Tissue.
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Rabbit Polyclonal to Human CXCR1
Human
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $355.00
CXCR1 Antibody - Staining of normal human peripheral blood cells with 0.25 ug of Purified Mouse IgG2b isotype control followed by PE Donkey F(ab')2 Fragment Anti-Mouse IgG (H+L, Minimal Reactivity to Rat IgG). Cells in the large scatter population were used for analysis.
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Mouse Monoclonal [clone 8F1-1-4] (IgG2b,k) to Human CXCR1
Human
Flo
Unconjugated
25µg   $205.00; 100µg   0.5mg/ml   $245.00
CXCR1 Antibody - Staining of normal human peripheral blood cells with PE anti-human CD182 (5E8-C7-F10) (LS-C106046) and FITC Mouse IgG2b isotype control. Cells in the large scatter population were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 8F1-1-4] (IgG2b,k) to Human CXCR1
Human
Flo
FITC Conjugated
25tst   $235.00; 100tst   $325.00
CXCR1 Antibody - Western blot of 15 ug of whole cell lysate from Raw cells with antibody at 2 ug/ml dilution.
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Rabbit Polyclonal (IgG) to Human CXCR1
Human
WB
Unconjugated
100µg   200µl   0.5mg/ml   $335.00
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Rabbit Polyclonal to Human CXCR1
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $325.00
CXCR1 Antibody
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Rabbit Polyclonal (IgG) to Human CXCR1
Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
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Rabbit Polyclonal (IgG) to Human CXCR1
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
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Rabbit Polyclonal (IgG) to Human CXCR1
Human
ELISA, IP, WB
Unconjugated
100µg   $375.00
CXCR1 Antibody - Western blot analysis of Human colon cancer and placenta tissue, using CXCR1 Polyclonal Antibody at dilution of 1:200.
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Rabbit Polyclonal (IgG) to Human CXCR1
Human
ELISA, WB
Unconjugated
20µl   0.4mg/ml   $205.00; 60µl   0.4mg/ml   $235.00; 120µl   0.4mg/ml   $295.00; 200µl   0.4mg/ml   $395.00

Viewing 1-25 of 32 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).