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CXCL5
chemokine (C-X-C motif) ligand 5
CXCL5 is a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.
| Gene Name: | chemokine (C-X-C motif) ligand 5 |
| Family/Subfamily: | Intercrine , Intercrine alpha |
| Synonyms: | CXCL5, C-X-C motif chemokine 5, ENA-78(1-78), GCP-2, ENA78, SCYB5, ENA-78, Small inducible cytokine B5, Small-inducible cytokine B5, LIX, AMCF-II |
| Target Sequences: | NM_002994 NP_002985.1 P42830 |
Publications (4)
1
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. Balamayoora Theivanthiran, Kathy S Evans, Nicholas C DeVito, Michael Plebanek, Michael Sturdivant, Luke P Wachsmuth, April Ks Salama, Yubin Kang, David Hsu, Justin M Balko, Douglas B Johnson, Mark Starr, Andrew B Nixon, Alisha Holtzhausen, Brent A Hanks. The Journal of clinical investigation. 2020 May;130:2570-2586. [Full Text Article]
[PubMed:32017708]
[PMC:PMC7190922]
Related Antibodies: LS-C293780.
2
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. Karim Mahiddine, Adam Blaisdell, Stephany Ma, Amandine Créquer-Grandhomme, Clifford A Lowell, Adrian Erlebacher. The Journal of clinical investigation. 2020 Jan;130:389-403. [Full Text Article]
[PubMed:31600172]
[PMC:PMC6934192]
Related Antibodies: LS-C212192.
3
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy. Nicholas C DeVito, Michael Sturdivant, Balamayooran Thievanthiran, Christine Xiao, Michael P Plebanek, April K S Salama, Georgia M Beasley, Alisha Holtzhausen, Veronica Novotny-Diermayr, John H Strickler, Brent A Hanks. Cell reports. 2021 May;35:109071. [Full Text Article]
[PubMed:33951424]
[PMC:PMC8148423]
Related Antibodies: LS-C104413.
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Publications
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(89)
Yes
(3)
CXCL5 Mouse anti-Human Monoclonal (2A9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$555
CXCL5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CXCL5 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CXCL5 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CXCL5 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CXCL5 Rabbit anti-Mouse Polyclonal (aa45-118) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
CXCL5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CXCL5 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CXCL5 Goat anti-Human Polyclonal Antibody
Human
ELISA, Func, IHC, IHC-P, Neut, WB
Unconjugated
100 µg/$962
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CXCL5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CXCL5 Rabbit anti-Rat Polyclonal (aa38-130) Antibody
Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
CXCL5 Rabbit anti-Mouse Polyclonal (aa41-132) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
CXCL5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$788
CXCL5 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µl/$937
CXCL5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$558
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
CXCL5 Mouse anti-Human Monoclonal (aa45-114) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
200 µl/$350
CXCL5 Mouse anti-Human Monoclonal (aa45-114) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
200 µl/$338
CXCL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CXCL5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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