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CXCL10 / IP-10

chemokine (C-X-C motif) ligand 10

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene Name: chemokine (C-X-C motif) ligand 10
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL10, C-X-C motif chemokine 10, Gamma-IP10, IP-10, Gamma IP10, GIP-10, Mob-1, Small-inducible cytokine B10, Crg-2, IFI10, INP10, SCYB10
Target Sequences: NM_001565 NP_001556.2 P02778

Publications (3)

1
Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment. Ren Luo, Elke Firat, Simone Gaedicke, Elena Guffart, Tsubasa Watanabe, Gabriele Niedermann. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 December;25:7243-7255. [Full Text Article] [PubMed:31506388] Related Antibodies: LS-C104402.
2
Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis. Chen Zou, Xiaozhi Lv, Haigang Wei, Siyuan Wu, Jing Song, Zhe Tang, Shiwei Liu, Xia Li, Yilong Ai. Bioengineered. 2022 March;13:6371-6382. [Full Text Article] [PubMed:35240924] [PMC:PMC8974029] Related Antibodies: LS-C104402.
3
Multiple halo nevi associated with Turner syndrome. Emi Yamazaki, Moyuka Irimada, Rui Sasaki, Kenichiro Tsuchiyama, Kenshi Yamasaki, Setsuya Aiba. The Journal of dermatology. 2021 Janurary;48:e11-e12. [Full Text Article] [PubMed:33063368] Related Antibodies: LS-C137619.

☰ Filters
Products
Proteins (36)
Over-Expression Lysate (2)
Recombinant (33)
CXCL10 / IP-10 (36)
SDS-PAGE (1)
Product Group
Coronavirus Antibodies Proteins cDNAs (36)
Cytokine Release Syndrome (36)
Cytokine Release Syndrome Proteins (36)
No (36)
6His, N-terminus (1)
Fc/6His,C-terminus (1)
Fc-6His, C-terminus (1)
GST (2)
His (3)
His, N-Terminal (2)
His-T7 (4)
Myc-DDK (Flag) (3)
Bovine (2)
Dog (1)
Human (19)
Mouse (6)
Pig (1)
Rabbit (1)
Rat (3)
Rhesus monkey (2)
293T Cells (1)
E. coli (25)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (2)
Wheat Germ Extract (1)
Yeast (4)
Purified (14)
Low endotoxin level (14)
Biologically active (12)
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.6 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.7 kDa
5 µg/$268; 25 µg/$349
CXCL10 / IP-10 Protein
Select
E. coli
None
Biologically active
8.7 kDa
5 µg/$296; 100 µg/$1,116; 500 µg/$2,095
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.6 kDa
5 µg/$268; 25 µg/$349
CXCL10 / IP-10 Protein - Purified recombinant protein CXCL10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
8.6 kDa
20 µg/$1,107
CXCL10 / IP-10 Protein - Recombinant Interferon Gamma Induced Protein 10kDa By SDS-PAGE
Select
E. coli
His, N-Terminal
10.1 kDa
10 µg/$339; 50 µg/$802; 100 µg/$1,214; 200 µg/$1,430; 1 mg/$2,728; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988
CXCL10 / IP-10 Protein - Recombinant Rabbit IP-10 detected using Goat anti Rabbit IP-10 as the capture reagent and Goat anti Rabbit IP-10:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
8.6 kDa
5 µg/$390
CXCL10 / IP-10 Protein - Recombinant Bovine IP-10 detected using Rabbit anti Bovine IP-10 as the capture reagent and Rabbit anti Bovine IP-10:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
9.3 kDa
5 µg/$390
CXCL10 / IP-10 Protein - Recombinant Pig IP-10 detected using Goat anti Pig IP-10 as the capture reagent and biotinylated Goat anti Pig IP-10 as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
9.3 kDa
5 µg/$390
Select
E. coli
None
Less than 0.01 EU/µg protein (determined by LAL method).
8.6 kDa
5 µg/$279; 20 µg/$354; 50 µg/$456; 100 µg/$634; 1000 µg/$2,337
CXCL10 / IP-10 Protein - Chemotaxis assay
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 78 amino acid recombinant protein has a predicted molecular mass of approximately 8.8 kD. The DTT-reduced and non-reduced protein migrate at approximately 10 kD by SDS-PAGE. The N-terminal amino acid is Met.
10 µg/$283; 25 µg/$355
CXCL10 / IP-10 Protein - PHA activated human T cells chemoattracted by human CXCL10.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 78 amino acid recombinant protein has a predicted molecular mass of approximately 8.7 kD. The DTT-reduced and non-reduced protein migrate at approximately 10 kD by SDS-PAGE. The N-terminal amino acid is Met.
10 µg/$283; 25 µg/$355; 100 µg/$607; 500 µg/$1,559
CXCL10 / IP-10 Protein
Select
E. coli
None
SDS-PAGE
The recombinant human CXCL10 consists of 78 amino acids and predicts a molecular mass of 8.8 KDa. It migrates as an approximately 9 KDa band in SDS-PAGE under reducing conditions.
100 µg/$480; 1 mg/$2,333; 20 µg/$317
CXCL10 / IP-10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
10.88 kDa
100 µg/$494
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.7 kDa
1 mg/$2,653; 25 µg/$364; 5 µg/$278
CXCL10 / IP-10 Protein - 12.5% SDS-PAGE of human CXCL10 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
36.52 kDa
2 µg/$439
CXCL10 / IP-10 Protein
Select
Yeast
His
10.65 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
GST
36.1 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CXCL10 / IP-10 Protein
Select
E. coli
His
12.8 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
8.6 kDa (SDS-PAGE)
50 µg/$342; 10 µg/$262; 1 mg/$1,395
CXCL10 / IP-10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, N-terminus
100 µg/$1,009; 20 µg/$431; 1 mg/$3,451
CXCL10 / IP-10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.88 kDa
20 µg/$150
CXCL10 / IP-10 Protein
Select
E. coli
None
Biologically active
8.6 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CXCL10 / IP-10 Protein
Select
E. coli
None
Biologically active
8.7 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CXCL10 / IP-10 Protein
Select
E. coli
None
Biologically active
8.7 kDa
5 µg/$296; 100 µg/$1,116; 500 µg/$2,095
Viewing 1-25 of 36 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).