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CXCL10 / IP-10

chemokine (C-X-C motif) ligand 10

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene Name: chemokine (C-X-C motif) ligand 10
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL10, C-X-C motif chemokine 10, Gamma-IP10, IP-10, Gamma IP10, GIP-10, Mob-1, Small-inducible cytokine B10, Crg-2, IFI10, INP10, SCYB10
Target Sequences: NM_001565 NP_001556.2 P02778

Publications (3)

1
Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment. Ren Luo, Elke Firat, Simone Gaedicke, Elena Guffart, Tsubasa Watanabe, Gabriele Niedermann. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 December;25:7243-7255. [Full Text Article] [PubMed:31506388] Related Antibodies: LS-C104402.
2
Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis. Chen Zou, Xiaozhi Lv, Haigang Wei, Siyuan Wu, Jing Song, Zhe Tang, Shiwei Liu, Xia Li, Yilong Ai. Bioengineered. 2022 March;13:6371-6382. [Full Text Article] [PubMed:35240924] [PMC:PMC8974029] Related Antibodies: LS-C104402.
3
Multiple halo nevi associated with Turner syndrome. Emi Yamazaki, Moyuka Irimada, Rui Sasaki, Kenichiro Tsuchiyama, Kenshi Yamasaki, Setsuya Aiba. The Journal of dermatology. 2021 Janurary;48:e11-e12. [Full Text Article] [PubMed:33063368] Related Antibodies: LS-C137619.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).