CXCL1 / GRO Alpha

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

GRO Alpha (CXCL1), a small cytokine belonging to the CXC chemokine family, secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. GRO alpha is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. GRO Alpha plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. An initial study in mice showed evidence that GRO alpha decreased the severity of multiple sclerosis and may offer a neuro-protective function.

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Products

Proteins (35)

Type

Recombinant (35)

Target

CXCL1 / GRO Alpha (35)

Publications

No (35)

Tag

6His, C-terminus (5)

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (3)

His, N-Terminal (2)

His-GST (2)

His-MBP (1)

His-T7 (1)

Species

Human (15)

Mouse (15)

Rat (4)

Source

293F Cells (1)

CHO Cells (1)

E. coli (25)

Human Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (3)

Purification

Purified (16)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (13)

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Human CXCL1 / GRO Alpha Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136987

Source:

E. coli

Tag:

6His, C-terminus

Molecular Weight:

10.6 kDa

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse CXCL1 / GRO Alpha Protein (Recombinant His, N-Terminal) (Ala25-Lys96) - LS-G132936

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

12kDa

Price:

10 µg/$315; 50 µg/$652; 200 µg/$1,228; 100 µg/$1,034; 1 mg/$2,469; 500 µg/$1,971; 5 mg/$4,551; 2 mg/$2,661

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Human CXCL1 / GRO Alpha Protein (Recombinant) - LS-G133841

Source:

E. coli

Tag:

None

Molecular Weight:

7.8 kDa

Price:

5 µg/$282; 25 µg/$370

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G137765

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 68 amino acid recombinant protein has a predicted molecular mass of approximately 7.4 kD. The DTT-reduced protein migrates at approximately 10 kD and non-reduced protein migrates at slightly higher than 10 kD by SDS-PAGE. The N-terminal amino acid is

Price:

10 µg/$325; 25 µg/$459; 500 µg/$2,640

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Human CXCL1 / GRO Alpha Protein (Recombinant GST, N-terminus) (aa36-107) - LS-G58766

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CXCL1 / GRO Alpha Protein (Recombinant His, N-Terminal) - LS-G144563

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

7.8 kDa

Price:

50 µg/$419

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G145752

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

7.8 kDa

Price:

1 mg/$2,653; 20 µg/$364

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Human CXCL1 / GRO Alpha Protein (Recombinant GST) (Full Length) - LS-G28723

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.51 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CXCL1 / GRO Alpha Protein (Recombinant GST) (Full Length) - LS-G28724

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse CXCL1 / GRO Alpha Protein (Recombinant His) (aa29-96) - LS-G22452

Source:

E. coli

Tag:

His

Molecular Weight:

11.6 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G37840

Tag:

None

Molecular Weight:

7.8 kD

Price:

20 µg/$476

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G27104

Source:

CHO Cells

Tag:

None

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

5-7 kDa (SDS-PAGE)

Price:

5 µg/$253; 25 µg/$296; 1 mg/$1,513

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Human CXCL1 / GRO Alpha Protein (Recombinant) (aa35-107) - LS-G5609

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

7.9 kDa

Price:

5 µg/$282; 100 µg/$957; 500 µg/$1,747

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) (aa25-96) - LS-G5653

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

7.8 kDa

Price:

5 µg/$282; 100 µg/$957; 500 µg/$1,747

Select

Rat CXCL1 / GRO Alpha Protein (Recombinant) (aa25-96) - LS-G5687

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

7.8 kDa

Price:

5 µg/$282; 100 µg/$957; 500 µg/$1,747

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Mouse CXCL1 / GRO Alpha Protein (Recombinant His) - LS-G1761

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G222

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

7.8 kDa

Price:

5 µg/$268; 20 µg/$349

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Human CXCL1 / GRO Alpha Protein (Recombinant) - LS-G266

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

7.8 kDa

Price:

5 µg/$268; 25 µg/$349

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Rat CXCL1 / GRO Alpha Protein (Recombinant) - LS-G398

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

7.8 kDa

Price:

5 µg/$268; 25 µg/$349

Select

Human CXCL1 / GRO Alpha Protein (Recombinant) - LS-G131244

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~8 kDa

Price:

25 µg/$291; 200 µg/$746; 1 mg/$2,551

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Human CXCL1 / GRO Alpha Protein (Recombinant) (Full Length) - LS-G136688

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

8.6 kDa

Price:

50 µg/$453; 10 µg/$288; 1 mg/$2,837; 500 µg/$1,987

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Rat CXCL1 / GRO Alpha Protein (Recombinant) - LS-G131574

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~8 kDa

Price:

25 µg/$291; 100 µg/$437; 1 mg/$1,587

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Mouse CXCL1 / GRO Alpha Protein (Recombinant) - LS-G131537

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~8 kDa

Price:

25 µg/$291; 100 µg/$462; 1 mg/$2,551

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Human CXCL1 / GRO Alpha Protein (Recombinant 6His, N-terminus) (Ala35-Asn107) - LS-G26985

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

11 kDa

Price:

50 µg/$314; 100 µg/$356; 200 µg/$473

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CXCL1 / GRO Alpha Protein (Recombinant) (Ala35-Asn107) - LS-G27009

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

7.8 kDa (SDS-PAGE)

Price:

5 µg/$273; 25 µg/$364; 1 mg/$1,513

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