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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CXCL1 / GRO Alpha

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

GRO Alpha (CXCL1), a small cytokine belonging to the CXC chemokine family, secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. GRO alpha is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. GRO Alpha plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. An initial study in mice showed evidence that GRO alpha decreased the severity of multiple sclerosis and may offer a neuro-protective function.

Gene Name: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL1, C-X-C motif chemokine 1, Fibroblast secretory protein, FSP, GRO1, GROa, Growth-regulated alpha protein, GRO-alpha(1-73), MGSA, MGSA-a, Small inducible cytokine b1, GRO, MGSA alpha, NAP-3, SCYB1
Target Sequences: NM_001511 NP_001502.1 P09341

Publications (2)

1
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFa-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, Yamori T, Shibasaki M, Nomoto A. PloS one. 2015 10:e0119415. (IHC; Human) [Full Text Article] [PubMed:25785838] [PMC:PMC4364666] Related Antibodies: LS-C104351.
2
Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study. Brochu ME, Girard S, Lavoie K, Sébire G. Journal of neuroinflammation. 2011 8:55. (WB; Rat) [Full Text Article] [PubMed:21599903]

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Target
CXCL1 / GRO Alpha (156)
Reactivity
Human (62)
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Bat (1)
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Horse (1)
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Application
IHC (71)
IHC-P (4)
WB (141)
ELISA (57)
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IP (3)
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Peptide-ELISA (2)
Host
rabbit (117)
mouse (38)
goat (1)
Isotype
IgG (108)
IgG1 (2)
IgG1,k (7)
IgG2a,k (1)
IgG2b,k (8)
IgM (1)
Clonality
monoclonal mc (38)
polyclonal pc (118)
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AP Conjugated (7)
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APC Conjugated (13)
Biotin Conjugated (22)
Cy3 Conjugated (8)
Cy7 Conjugated (8)
FITC Conjugated (20)
HRP Conjugated (17)
PE Conjugated (15)
Unconjugated (46)
Epitope
aa25-96 (34)
aa35-107 (9)
C-Terminus (5)
N-Terminus (3)
aa36-107 (3)
Internal (1)
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aa39-88 (1)
aa98-107 (1)
aa99-107 (1)
Publications
No (155)
Yes (1)
Showing 1-25 of 156 results

CXCL1 / GRO Alpha Antibody IHC-plus™ LS-B2843
Rabbit Polyclonal to Human CXCL1 / GRO Alpha
Human
ELISA IHC IHC-P Neut WB
Unconjugated
100µg 1mg/ml  $485.00
Anti-GRO Alpha antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-GRO Alpha antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

CXCL1 / GRO Alpha Antibody LS-C104351
Publications (1)
Publications (1)
Rabbit Polyclonal to Human CXCL1 / GRO Alpha
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody (aa36-107, clone 7A11) LS-C125418
Mouse Monoclonal [clone 7A11] (IgG) to Human CXCL1 / GRO Alpha
Human
ELISA WB
Unconjugated
100µg 1mg/ml  $590.00

CXCL1 / GRO Alpha Antibody LS-C48831
Rabbit Polyclonal to Rat CXCL1 / GRO Alpha
Mouse, Rat
IHC IP WB
Unconjugated
100µg 200µl 0.5mg/ml  $465.00
Western blot of GRO / CXCL1 antibody.
Western blot of GRO / CXCL1 antibody.

CXCL1 / GRO Alpha Antibody LS-C104778
Rabbit Polyclonal to Rat CXCL1 / GRO Alpha
Rat
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody (Biotin) LS-C104777
Rabbit Polyclonal to Rat CXCL1 / GRO Alpha
Rat
ELISA WB
Biotin Conjugated
25µg  $285.00; 50µg  $325.00
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody (clone 2D7) LS-C139335
Mouse Monoclonal [clone 2D7] (IgG2a,k) to Human CXCL1 / GRO Alpha
Human
ELISA
Unconjugated
100µg 0.5mg/ml  $355.00
Detection limit for recombinant GST tagged CXCL1 is 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CXCL1 is 1 ng/ml as a capture antibody.

CXCL1 / GRO Alpha Antibody LS-C104609
Rabbit Polyclonal to Mouse CXCL1 / GRO Alpha
Mouse
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody (Biotin) LS-C104613
Rabbit Polyclonal to Mouse CXCL1 / GRO Alpha
Mouse
ELISA WB
Biotin Conjugated
25µg  $285.00; 50µg  $325.00
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (non-reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of GRO / CXCL1 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody LS-C212186
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
ELISA WB
Unconjugated
50µg  $285.00; 100µg 1mg/ml  $385.00

CXCL1 / GRO Alpha Antibody (HRP) LS-C212191
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
ELISA IHC WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00

CXCL1 / GRO Alpha Antibody (Biotin) LS-C212194
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
ELISA IHC WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

CXCL1 / GRO Alpha Antibody (FITC) LS-C212195
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
ELISA WB
FITC Conjugated
50µg  $285.00; 100µg 0.25mg/ml  $385.00

CXCL1 / GRO Alpha Antibody (aa36-107) LS-C137618
Mouse Monoclonal (IgG1) to Human CXCL1 / GRO Alpha
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot Image
Western blot Image

CXCL1 / GRO Alpha Antibody (Pro88) LS-C177218
Rabbit Polyclonal to Human CXCL1 / GRO Alpha
Mouse, Rat, Human
IHC IHC-P
Unconjugated
100µl  $345.00
IHC of GRO (P88) pAb in paraffin-embedded human brain tissue.
IHC of GRO (P88) pAb in paraffin-embedded human brain tissue.

CXCL1 / GRO Alpha Antibody (Internal) IHC-plus™ LS-B14347
Rabbit Polyclonal (IgG) to Human CXCL1 / GRO Alpha
Mouse, Rat, Human
ELISA IHC IHC-P
Unconjugated
50µl 1mg/ml  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

CXCL1 / GRO Alpha Antibody (N-Terminus) LS-C193999
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC IHC-P WB
Unconjugated
100µg 1ml  $860.00

CXCL1 / GRO Alpha Antibody LS-C665997
Rabbit Polyclonal (IgG) to Human CXCL1 / GRO Alpha
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

CXCL1 / GRO Alpha Antibody LS-C193997
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC WB
Unconjugated
500µg 1ml  $860.00

CXCL1 / GRO Alpha Antibody LS-C193998
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC WB
Unconjugated
100µg 1ml  $860.00

CXCL1 / GRO Alpha Antibody (aa25-96) LS-C295614
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $275.00; 1ml 0.5mg/ml  $445.00; 10ml 0.5mg/ml  $1,725.00
Western blot of recombinant GRO / CXCL1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant GRO / CXCL1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CXCL1 / GRO Alpha Antibody (aa25-96) LS-C372412
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $275.00; 1ml 0.5mg/ml  $445.00; 10ml 0.5mg/ml  $1,725.00
Western blot of GRO / CXCL1 antibody.
Western blot of GRO / CXCL1 antibody.

CXCL1 / GRO Alpha Antibody (aa25-96) LS-C372413
Rabbit Polyclonal (IgG) to Mouse CXCL1 / GRO Alpha
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $275.00; 1ml 0.5mg/ml  $445.00; 10ml 0.5mg/ml  $1,725.00
Western blot of GRO / CXCL1 antibody.
Western blot of GRO / CXCL1 antibody.

CXCL1 / GRO Alpha Antibody LS-C412516
Rabbit Polyclonal to Human CXCL1 / GRO Alpha
Mouse, Human
IHC WB
Unconjugated
100µl  $385.00

CXCL1 / GRO Alpha Antibody (aa35-107) LS-C295613
Rabbit Polyclonal (IgG) to Human CXCL1 / GRO Alpha
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $185.00; 100µl 0.5mg/ml  $225.00; 200µl 0.5mg/ml  $245.00; 1ml 0.5mg/ml  $385.00; 10ml 0.5mg/ml  $1,320.00
Western blot of recombinant GRO / CXCL1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant GRO / CXCL1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 156 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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