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CXADR

coxsackie virus and adenovirus receptor

Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Gene Name: coxsackie virus and adenovirus receptor
Synonyms: CXADR, CAR4/6, Coxsackie-adenovirus receptor, CVB3-binding protein, CAR, HCAR, HCVADR
Target Sequences: NM_001338 NP_001329.1 P78310

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Products
Antibodies (59)
Primary (59)
CXADR (59)
Human (56)
Mouse (22)
Rat (32)
Bat (4)
Bovine (1)
Chimpanzee (3)
Gibbon (3)
Guinea pig (1)
Hamster (1)
Horse (1)
Monkey (1)
Orangutan (3)
Pig (1)
Rabbit (4)
IHC (15)
IHC-P (8)
WB (41)
Flo (4)
ELISA (17)
ICC (11)
IF (4)
IP (2)
Peptide-ELISA (3)
rabbit (52)
mouse (7)
Product Group
IHCPlus (4)
IgG (26)
IgG1 (7)
monoclonal mc (8)
polyclonal pc (51)
023 (1)
APC (1)
APC Conjugated (3)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (5)
PE Conjugated (4)
Preservative Free (2)
Unconjugated (34)
aa20-229 (8)
aa72-121 (4)
Internal (2)
10-90 aa, N-terminal (1)
N-Terminus (1)
aa1-50 (1)
aa132-161 (1)
aa16-44 (1)
aa300-335 (1)
aa313-328 (1)
aa335-365 (1)
aa38-87 (1)
aa48-93 (1)
No (59)
CXADR Antibody - Anti-CXADR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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CXADR Mouse anti-Human Monoclonal Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$705
CXADR Antibody - Anti-CXADR antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CXADR Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
CXADR Antibody - Anti-CXADR antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CXADR Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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CXADR Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
200 µg/$872
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CXADR Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Rat, Human
ICC, WB
Biotin Conjugated
100 µl/$1,089
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CXADR Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Rat, Human
ICC, WB
PE Conjugated
100 µl/$1,089
CXADR Antibody - WB of CXADR antibody. Lane 1: Rat Pancreas Tissue Lysate. Lane 2: Rat Brain Tissue Lysate. Lane 3: Rat Heart Tissue Lysate. Lane 4: HELA Cell Lysate. Lane 5: 293T Cell Lysate. Lane 6: COLO320 Cell Lysate.
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CXADR Rabbit anti-Human Polyclonal (aa313-328) Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
CXADR Antibody - Western blot of anti-CXADR Antibody in NCI-H460 cell line lysates (35 ug/lane). CXADR(arrow) was detected using the purified antibody.
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CXADR Rabbit anti-Human Polyclonal (aa132-161) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
CXADR Antibody - Western blot of CAR antibody
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CXADR Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CXADR Antibody - Anti-CXADR antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CXADR Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CXADR Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
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CXADR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CXADR Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CXADR Rabbit anti-Human Polyclonal (aa16-44) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CXADR Rabbit anti-Human Monoclonal (Preservative Free) (023) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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CXADR Rabbit anti-Human Polyclonal (FITC) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
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CXADR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, ICC, IF
Unconjugated
20 µl/$271; 100 µl/$412
CXADR Antibody - Immunochemical staining of human CXADR in human bladder carcinoma with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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CXADR Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
CXADR Antibody - Immunofluorescent analysis of CXADR staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CXADR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
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CXADR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
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CXADR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
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CXADR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CXADR Antibody - Detection of Human CAR by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CAR used at a dilution of 1:200 (1 ug/ml). Detection: Vector Laboratories ImmPACT NovaRED Peroxidase Substrate.
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CXADR Rabbit anti-Human Polyclonal (aa300-335) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CXADR Antibody - Detection of Human CAR by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CAR used at a dilution of 1:1000 (1 ug/ml). Detection: Vector Laboratories ImmPACT NovaRED Peroxidase Substrate.
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CXADR Rabbit anti-Human Polyclonal (aa335-365) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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CXADR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CXADR Antibody - Western blot analysis of extracts of various cell lines.
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CXADR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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CXADR Rabbit anti-Human Polyclonal (aa48-93) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).