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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CX3CR1

chemokine (C-X3-C motif) receptor 1

CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.

Gene Name: chemokine (C-X3-C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: CX3CR1, Beta chemokine receptor-like 1, C-X3-C CKR-1, Chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL-1, CMKDR1, CMK-BRL1, CX3C chemokine receptor 1, Fkn receptor, GPR13, GPRV28, Fractalkine receptor, G protein-coupled receptor v28, G-protein coupled receptor 13, V28, Chemokine c-x3-c receptor 1, G protein-coupled receptor 13
Target Sequences: NM_001337 NP_001328.1 P49238

Publications (2)

1
Up-regulation of CX3CR1 on tonsillar CD8-positive cells in patients with IgA nephropathy. Otaka R, Takahara M, Ueda S, Nagato T, Kishibe K, Nomura K, Katada A, Hayashi T, Harabuchi Y. Human immunology. 2017 78:375-383. (IHC; Human) [Full Text Article] [PubMed:28196748] Related Antibodies: LS-A86.
2
High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation. Szukiewicz D, Pyzlak M, Szewczyk G, Stangret A, Trojanowski S, Bachanek M, Braksator W, Wejman J. Mediators of inflammation. 2017 2017:9853108. [Full Text Article] [PubMed:28655972] [PMC:PMC5471565]

Filtered by: None
Target
CX3CR1 (73)
Reactivity
Human (70)
Mouse (21)
Rat (21)
Application
IHC (33)
IHC-P (10)
WB (53)
Flo (12)
ELISA (22)
IF (7)
IP (1)
Peptide-ELISA (2)
Host
rabbit (64)
mouse (3)
goat (2)
rat (4)
Isotype
IgG (49)
IgG1 (1)
IgG2a,k (1)
IgG2b (1)
IgG2b,k (3)
Clonality
monoclonal mc (6)
polyclonal pc (67)
Clone
2A9-1 (4)
2B11 (1)
Format
AP Conjugated (6)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (9)
FITC Conjugated (9)
HRP Conjugated (8)
PE Conjugated (8)
Unconjugated (29)
Epitope
Extracellular Domain (8)
aa39-69 (7)
C-Terminus (5)
N-Terminus (3)
120-200 aa, Internal (1)
270-350 aa, C-terminal (1)
Internal (1)
N-Terminal (1)
aa291-340 (1)
aa34-47 (1)
Publications
No (72)
Yes (1)
Showing 1-25 of 73 results

IHC-plus™ CX3CR1 Antibody (Extracellular Domain) LS-A86
Publications (1)
Publications (1)
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, Biotin) LS-A108097
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
Biotin Conjugated
100µl 0.85mg/ml  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, FITC) LS-A108098
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
FITC Conjugated
100µl 0.9mg/ml  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, Azide-free, HRP) LS-A108099
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, APC) LS-A108096
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, AP) LS-A108095
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ CX3CR1 Antibody (Extracellular Domain, PE) LS-A108100
Rabbit Polyclonal to Human CX3CR1
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CX3CR1 Antibody LS-C300
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1mg 1mg/ml  $365.00
IHC of human heart tissue using CX3CR1 antibody at 2 ug/ml.
Immunohistochemistry of CX3CR1 in mouse heart tissue with CX3CR1 antibody at 2 µg/ml.

CX3CR1 Antibody (Extracellular Domain, PE) LS-C125420
Mouse Monoclonal (IgG1) to Human CX3CR1
Human
Flo
PE Conjugated
100tst  $695.00

CX3CR1 Antibody LS-C325
Rabbit Polyclonal (IgG) to Human CX3CR1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1mg 1mg/ml  $365.00
Immunohistochemistry of CX3CR1 in human spleen cells with CX3CR1 antibody at 10 µg/ml.
Immunofluorescence of CX3CR1 in THP1 cells with CX3CR1 antibody at 20 ug/ml.

CX3CR1 Antibody (N-Terminus) LS-C125421
Goat Polyclonal (IgG) to Mouse CX3CR1
Mouse
Flo, WB
Unconjugated
100µg  $785.00

CX3CR1 Antibody (clone 2A9-1, Biotin) LS-C106166
Rat Monoclonal [clone 2A9-1] (IgG2b) to Human CX3CR1
Human
Flo
Biotin Conjugated
25µg 0.5mg/ml  $265.00; 100µg 0.5mg/ml  $365.00
Staining of normal human peripheral blood cells with 0.125 ug Biotin Rat IgG1 isotype control (left) or 0.125 ug Biotin anti-human CX3CR1 (right) followed by PE-streptavidin. Samples were subsequently stained intracellularly with FITC anti-human Perforin (dG9). Cells were gated on CD16+CD56+ using eFluor 450 anti-human CD16 and APC anti-human CD56 (LS-C107245). This image was taken for the unconjugated form of this product. Other forms have not been tested.

CX3CR1 Antibody LS-C170822
Rabbit Polyclonal to Human CX3CR1
ELISA, IHC, WB
Unconjugated
100µg  $365.00

CX3CR1 Antibody (Biotin) LS-C525309
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
Flo, IHC, WB
Biotin Conjugated
100µl  $965.00

CX3CR1 Antibody (FITC) LS-C535327
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
Flo, IHC, WB
FITC Conjugated
100µl  $965.00

CX3CR1 Antibody (APC) LS-C516232
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
Flo, IHC, WB
APC Conjugated
100µl  $965.00

CX3CR1 Antibody (PE) LS-C653509
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
Flo, IHC, WB
PE Conjugated
100µl  $965.00

CX3CR1 Antibody (clone 2B11) LS-C197005
Mouse Monoclonal [clone 2B11] (IgG2a,k) to Human CX3CR1
Human
ELISA, WB
Unconjugated
100µg  $365.00
Detection limit for recombinant GST tagged CX3CR1 is approximately 10 ng/ml as a capture antibody.

CX3CR1 Antibody (C-Terminus) LS-C354390
Rabbit Polyclonal to Human CX3CR1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of GPR13 expression in MCF7 (A); NS-1 (B); PC12 (C) whole cell lysates.

CX3CR1 Antibody LS-C664878
Rabbit Polyclonal (IgG) to Human CX3CR1
Human
ELISA, Flo, IHC, WB
Unconjugated
100µg  $335.00

CX3CR1 Antibody (270-350 aa, C-terminal) LS-C382956
Rabbit Polyclonal (IgG) to Human CX3CR1
Human
ELISA, IF, IHC
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

CX3CR1 Antibody LS-C498674
Rabbit Polyclonal (IgG) to Human CX3CR1
Human
ELISA, IF, IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human heart tissue using CX3CR1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CX3CR1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CX3CR1 Antibody (aa291-340) LS-C291468
Rabbit Polyclonal (IgG) to Human CX3CR1
Human
IF, IHC, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00

CX3CR1 Antibody LS-C809143
Rabbit Polyclonal (IgG) to Human CX3CR1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

CX3CR1 Antibody (N-Terminus) LS-C6278
Rabbit Polyclonal (IgG) to Rat CX3CR1
Rat
IHC, IP, WB
Unconjugated
100µg  $455.00
Showing 1-25 of 73 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).