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CX3CL1 / Fractalkine
chemokine (C-X3-C motif) ligand 1
CX3CL1/fractalkine is a chemokine with a unique CX3C motif. Fractalkine is synthesized in endothelial cells as a membrane protein, and the N-terminal domain containing a CX3C motif is cleaved and secreted. Fractalkine is the first described cell-surface anchored chemokine and has potent mononuclear cell-directed adhesion and chemotactic properties. Fractalkine is involved in the pathogenesis of various chronic inflammatory diseases, such as rheumatoid arthritis and atherosclerosis.
| Gene Name: | chemokine (C-X3-C motif) ligand 1 |
| Family/Subfamily: | Intercrine , Intercrine delta |
| Synonyms: | CX3CL1, ABCD-3, C-X3-C motif chemokine 1, C3Xkine, Chemokine ntt, CXC3C, FKN, Fractalkine, Neurotactin, CXC3, NTN, SCYD1, Small-inducible cytokine D1 |
| Target Sequences: | NM_002996 NP_002987.1 P78423 |
☰ Filters
Products
Proteins
(25)
Type
Recombinant
(25)
Target
CX3CL1 / Fractalkine
(25)
Publications
No
(25)
Tag
6His, C-terminus
(4)
DDK,C-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(4)
His-SUMO
(1)
His-T7
(1)
Human IgG1 Fc
(1)
Species
Human
(16)
Mouse
(5)
Rat
(3)
Source
CHO Cells
(2)
E. coli
(15)
HEK 293 Cells
(1)
Human Cells
(2)
Mammalian Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(13)
Low Endotoxin Level
Low endotoxin level
(14)
Biologically Active
Biologically active
(10)
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 85 amino acid recombinant protein has a predicted molecular mass of approximately 9.59 kD. The DTT-reduced protein migrates at approximately 13 kD and non-reduced protein migrates at 15.5 kD by SDS-PAGE. The N-terminal amino acid is Meteonine.
10 µg/$306; 25 µg/$375; 100 µg/$731
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.36kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.3kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
E. coli
His-SUMO
24.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His
28.2 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His
27.2 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
E. coli
His-T7
28.2 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His
28.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
50-75 kDa (SDS-PAGE)
5 µg/$262; 25 µg/$304; 1 mg/$1,740
Wheat Germ Extract
GST
69.41 kDa
10 µg/$479; 25 µg/$670
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 77 amino acid recombinant protein has a predicted molecular mass of approximately 8.77 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein migrates at 15.5 kD by SDS-PAGE. The N-terminal amino acid is Met.
10 µg/$306; 25 µg/$375; 100 µg/$731
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.3 kDa
10 µg/$281; 50 µg/$389
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.4 kDa
10 µg/$297; 50 µg/$460
HEK 293 Cells
DDK,C-terminus
Less than 0.06 EU/µg protein (determined by LAL method).
~50 kDa (SDS-PAGE)
10 µg/$337; 50 µg/$587
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.6 kDa
1 mg/$2,880; 20 µg/$372
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8.9 kDa
20 µg/$395; 1 mg/$4,915
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$511; 500 µg/$1,348; 20 µg/$311
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$480
E. coli
None
Biologically active
8.7 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
8.8 kDa
5 µg/$282; 500 µg/$2,095; 100 µg/$1,116
E. coli
None
Biologically active
8.6 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.5 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.7 kDa
5 µg/$268; 20 µg/$349
Viewing 1-25
of 25
product results
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