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CTSS / Cathepsin S
cathepsin S
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
| Gene Name: | cathepsin S |
| Family/Subfamily: | Protease , Cysteine C1 |
| Synonyms: | CTSS, Cathepsin S, Cat-s, CATS |
| Target Sequences: | NM_004079 NP_004070.3 P25774 |
Publications (1)
1
Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro. Charlotte M Flynn, Yvonne Garbers, Stefan Düsterhöft, Rielana Wichert, Juliane Lokau, Christian H K Lehmann, Diana Dudziak, Bernd Schröder, Christoph Becker-Pauly, Stefan Rose-John, Samadhi Aparicio-Siegmund, Christoph Garbers. Scientific reports. 2020 December;10:21612. [Full Text Article]
[PubMed:33303781]
[PMC:PMC7730449]
Related Antibodies: LS-C348945.
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Proteins
(15)
Type
Over-Expression Lysate
(2)
Recombinant
(13)
Target
CTSS / Cathepsin S
(15)
Publications
No
(15)
Tag
6His, C-terminus
(3)
GST
(1)
His
(6)
His,C-terminus
(1)
His-S
(1)
His-T7
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Human
(8)
Mouse
(5)
Source
293T Cells
(1)
E. coli
(6)
HEK 293 Cells
(2)
Human Cells
(3)
Mammalian Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(6)
E. coli
His-S
29.3 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.5kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
37 kDa
50 µg/$854
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.89kD
10 µg/$281
E. coli
His
25.5 kDa
10 µg/$272; 50 µg/$387; 100 µg/$620; 200 µg/$772; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016
E. coli
His-T7
27.5 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
27.8 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
E. coli
His
28.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST
62.15 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
37.3 kDa
100 µg/$494
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.5 kDa
10 µg/$317; 50 µg/$524
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
73.1 kDa
10 µg/$368; 50 µg/$479
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
293T Cells
Myc-DDK (Flag)
37.3 kDa
20 µg/$150
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
37.6 kDa
50 µg/$997
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