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CTSF / Cathepsin F

cathepsin F

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

Gene Name: cathepsin F
Family/Subfamily: Protease , Cysteine C1
Synonyms: CTSF, CATSF, CLN13, Cathepsin F
Target Sequences: NM_003793 NP_003784.2 Q9UBX1

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Products
Antibodies (20)
Primary (20)
CTSF / Cathepsin F (20)
Human (12)
Mouse (13)
Rat (3)
Monkey (2)
IHC (7)
IHC-P (5)
WB (19)
Flo (1)
ELISA (5)
Peptide-ELISA (2)
rabbit (19)
goat (1)
Product Group
IHCPlus (1)
IgG (8)
polyclonal pc (20)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
Internal (1)
aa261-290 (1)
aa472-484 (1)
No (20)
CTSF / Cathepsin F Antibody - CTSF Antibody (Center D276) IHC of formalin-fixed and paraffin-embedded human Skeletal muscle tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the CTSF Antibody (Center D276) for immunohistochemistry.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal (aa261-290) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CTSF / Cathepsin F Antibody - Western blot analysis of Cathepsin F expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
CTSF / Cathepsin F Antibody - Anti-CTSF / Cathepsin F antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CTSF / Cathepsin F Antibody - Anti-CTSF / Cathepsin F antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CTSF / Cathepsin F Antibody - Anti-CTSF / Cathepsin F antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CTSF / Cathepsin F Antibody - Anti-CTSF / Cathepsin F antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CTSF / Cathepsin F Antibody - Western blot analysis of extracts of mouse brain tissue using CathepsinF antibody. The lane on the left was treated with blocking peptide.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CTSF / Cathepsin F Antibody - Antibody (0.3 ug/ml) staining of Human Ovary lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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CTSF / Cathepsin F Goat anti-Human Polyclonal (aa472-484) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
CTSF / Cathepsin F Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using CTSF Polyclonal Antibody at dilution of 1:100 (40x lens).
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
CTSF / Cathepsin F Antibody
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CTSF / Cathepsin F Rabbit anti-Mouse Polyclonal (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CTSF / Cathepsin F Antibody - Western blot of CTSF antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: H9C2 whole cell lysate.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CTSF / Cathepsin F Antibody - Western blot analysis of extracts of various cell lines, using CTSF antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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CTSF / Cathepsin F Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).