Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CTSC / Cathepsin C / JP

cathepsin C

CTSC / Cathepsin C / JP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: cathepsin C
Family/Subfamily: Protease , Cysteine C1
Synonyms: CTSC, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase I, DPP-I, Dipeptidyl transferase, Dipeptidyl-peptidase I, CPPI, DPPI, DPP1, HMS, JP, PDON1, PLS, JPD, Cathepsin C, PALS
Target Sequences: NM_001814 NP_001805.3 P53634

Publications (1)

1
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence. Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper DS. Carcinogenesis. 2015 November;36:1263-1274. [Full Text Article] [PubMed:26354777]


CTSC / Cathepsin C / JP Antibody - Anti-CTSC / Cathepsin C / JP antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Goat Polyclonal to Human CTSC / Cathepsin C / JP
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
CTSC / Cathepsin C / JP Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal (IgG2b) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $425.00
Select
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Unconjugated
1mg   $485.00
CTSC / Cathepsin C / JP Antibody - Western blot of Human HCT15. CTSC antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Rabbit, Pig, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Select
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Unconjugated
10mg   $295.00
Select
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Biotin Conjugated
1ml   $405.00
CTSC / Cathepsin C / JP Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using CTSC Polyclonal Antibody at dilution of 1:50.
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, WB
Unconjugated
20µl   1.2mg/ml   $205.00; 60µl   1.2mg/ml   $235.00; 120µl   1.2mg/ml   $295.00; 200µl   1.2mg/ml   $395.00
CTSC / Cathepsin C / JP Antibody - Immunohistochemistry of paraffin-embedded human stomach tissue.
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
IHC, WB
Unconjugated
20µl   $215.00; 50µl   $255.00; 100µl   $315.00; 200µl   $425.00
CTSC / Cathepsin C / JP Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
CTSC / Cathepsin C / JP Antibody - Western blot of Cleaved-Cathepsin C HC (R394) antibody
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
CTSC / Cathepsin C / JP Antibody - Western blot analysis of extracts from Jurkat cells, treated with etoposide (25uM, 1hour), using Dipeptidyl-peptidase 1 (heavy chain, Cleaved-Arg394) antibody.
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, WB
Unconjugated
1mg   1mg/ml   $305.00
CTSC / Cathepsin C / JP Antibody - Western blot of extracts from Jurkat cells, treated with etoposide 25 uM 1h, using Dipeptidyl-peptidase 1 (heavy chain, Cleaved-Arg394) Antibody. The lane on the right is treated with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
CTSC / Cathepsin C / JP Antibody - Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $545.00
CTSC / Cathepsin C / JP Antibody - Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
HRP Conjugated
200µl   0.5mg/ml   $345.00; 500µl   0.5mg/ml   $560.00; 1ml   0.5mg/ml   $695.00
CTSC / Cathepsin C / JP Antibody - Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
FITC Conjugated
200µl   0.5mg/ml   $365.00; 500µl   0.5mg/ml   $605.00; 1ml   0.5mg/ml   $755.00
CTSC / Cathepsin C / JP Antibody - Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
PE Conjugated
200µl   0.1mg/ml   $650.00; 500µl   0.1mg/ml   $1,290.00; 1ml   0.1mg/ml   $1,620.00
Select
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
WB
Unconjugated
100µg   $605.00
CTSC / Cathepsin C / JP Antibody - CTSC / Cathepsin C antibody Western blot of PANC1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Bovine, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
CTSC / Cathepsin C / JP Antibody - Western blot of CTSC antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $385.00
CTSC / Cathepsin C / JP Antibody - Western blot of CTSC antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $385.00
CTSC / Cathepsin C / JP Antibody - Western blot analysis of Cathepsin C LC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00
CTSC / Cathepsin C / JP Antibody - Western blot analysis of Cathepsin C HC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00
CTSC / Cathepsin C / JP Antibody - Western blot analysis of Cathepsin C HC expression in H9C2 (A), PC3 (B) whole cell lysates.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Rat, Human
WB
Unconjugated
30µl   1mg/ml   $205.00; 100µl   1mg/ml   $245.00; 200µl   1mg/ml   $305.00
CTSC / Cathepsin C / JP Antibody - Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Human
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $530.00
Viewing 1-25 of 52 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).