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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTSC / Cathepsin C / JP

cathepsin C

CTSC / Cathepsin C / JP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: cathepsin C
Family/Subfamily: Protease , Cysteine C1
Synonyms: CTSC, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase I, DPP-I, Dipeptidyl transferase, Dipeptidyl-peptidase I, CPPI, DPPI, DPP1, HMS, JP, PDON1, PLS, JPD, Cathepsin C, PALS
Target Sequences: NM_001814 NP_001805.3 P53634

Filtered by: None
Target
CTSC / Cathepsin C / JP (52)
Reactivity
Human (41)
Mouse (26)
Rat (7)
Bat (4)
Bovine (9)
Chimpanzee (3)
Dog (2)
Gibbon (6)
Monkey (9)
Orangutan (6)
Pig (4)
Rabbit (4)
Application
IHC (10)
IHC-P (3)
WB (48)
ELISA (8)
IF (3)
Peptide-ELISA (2)
Host
rabbit (49)
mouse (2)
goat (1)
Isotype
IgG (18)
IgG2b (1)
Clonality
monoclonal mc (1)
polyclonal pc (51)
Format
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (22)
Epitope
aa231-462 (8)
aa231-463 (8)
aa151-200 (4)
aa185-234 (4)
320-400 aa, C-terminal (1)
C-Terminus (1)
Internal (1)
aa238-252 (1)
aa345-394 (1)
Publications
No (52)
Showing 1-25 of 52 results

IHC-plus™ CTSC / Cathepsin C / JP Antibody (aa238-252) LS-B10387
Goat Polyclonal to Human CTSC / Cathepsin C / JP
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-CTSC / Cathepsin C / JP antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-CTSC / Cathepsin C / JP antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CTSC / Cathepsin C / JP Antibody LS-C147357
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Unconjugated
1mg  $475.00

CTSC / Cathepsin C / JP Antibody LS-C406268
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, WB
Unconjugated
20µl 1.3mg/ml  $205.00; 60µl 1.3mg/ml  $235.00; 120µl 1.3mg/ml  $295.00; 200µl 1.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human Lymphoma using CTSC Polyclonal Antibody at dilution of 1:25.
Western blot analysis of Human placenta tissue, using CTSC Polyclonal Antibody at dilution of 1:350.

IHC-plus™ CTSC / Cathepsin C / JP Antibody LS-B9359
Mouse Monoclonal (IgG2b) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-CTSC / Cathepsin C / JP antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

CTSC / Cathepsin C / JP Antibody (aa151-200) LS-C187240
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Rabbit, Pig, Bat, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
Western blot of Human HCT15. CTSC antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody LS-C147355
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Unconjugated
10mg  $285.00

CTSC / Cathepsin C / JP Antibody (Biotin) LS-C147356
Rabbit Polyclonal to Bovine CTSC / Cathepsin C / JP
Bovine
ELISA, IF, IHC, WB
Biotin Conjugated
1ml  $395.00

CTSC / Cathepsin C / JP Antibody LS-C403028
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, WB
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CTSC Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human liver cancer using CTSC Polyclonal Antibody at dilution of 1:50.

CTSC / Cathepsin C / JP Antibody LS-C670038
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CTSC / Cathepsin C / JP Antibody LS-C409938
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl  $255.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human stomach tissue.
Immunohistochemistry of paraffin-embedded rat kidney tissue.

CTSC / Cathepsin C / JP Antibody LS-C765880
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

CTSC / Cathepsin C / JP Antibody (320-400 aa, C-terminal) LS-C380474
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
ELISA, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Cleaved-Cathepsin C HC (R394) antibody

CTSC / Cathepsin C / JP Antibody (aa345-394) LS-C121074
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot of extracts from Jurkat cells, treated with etoposide 25 uM 1h, using Dipeptidyl-peptidase 1 (heavy chain, Cleaved-Arg394) Antibody. The lane on the right is treated with the synthesized peptide.

CTSC / Cathepsin C / JP Antibody (aa231-462) LS-C293247
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00
Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody (aa231-462, HRP) LS-C712091
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
HRP Conjugated
100µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $345.00; 1ml 0.5mg/ml  $695.00
Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody (aa231-462, Cy3) LS-C703065
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
Cy3 Conjugated
100µl 0.1mg/ml  $365.00; 200µl 0.1mg/ml  $445.00; 1ml 0.1mg/ml  $1,080.00
Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody (aa231-462, PE) LS-C726148
Rabbit Polyclonal to Mouse CTSC / Cathepsin C / JP
Mouse
WB
PE Conjugated
100µl 0.1mg/ml  $255.00; 200µl 0.1mg/ml  $285.00; 1ml 0.1mg/ml  $485.00
Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody LS-C309728
Rabbit Polyclonal (IgG) to Human CTSC / Cathepsin C / JP
Human
WB
Unconjugated
100µg  $605.00

CTSC / Cathepsin C / JP Antibody (aa185-234) LS-C135714
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Bovine, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
CTSC / Cathepsin C antibody Western blot of PANC1 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTSC / Cathepsin C / JP Antibody (Internal) LS-C354305
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Cathepsin C HC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

CTSC / Cathepsin C / JP Antibody (C-Terminus) LS-C354303
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Cathepsin C LC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

CTSC / Cathepsin C / JP Antibody LS-C411818
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of CTSC antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

CTSC / Cathepsin C / JP Antibody LS-C411820
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of CTSC antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

CTSC / Cathepsin C / JP Antibody LS-C761075
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Rat, Human
WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Western blot analysis of Cathepsin C HC expression in H9C2 (A), PC3 (B) whole cell lysates.

CTSC / Cathepsin C / JP Antibody (aa231-463) LS-C293246
Rabbit Polyclonal to Human CTSC / Cathepsin C / JP
Mouse, Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of recombinant CTSC / Cathepsin C / JP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Human Placenta lysate; Primary Ab: 2µg/ml Rabbit Anti-Human CTSC Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Showing 1-25 of 52 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).