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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTR9

CTR9, Paf1/RNA polymerase II complex component

Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Required for mono- and trimethylation on histone H3 'Lys-4' (H3K4me3) and dimethylation on histone H3 'Lys-79' (H3K4me3). Required for Hox gene transcription. Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of the SET1 complex. Involved in transcriptional regulation of IL6-responsive genes and in JAK-STAT pathway; may regulate DNA-association of STAT3.

Gene Name: CTR9, Paf1/RNA polymerase II complex component
Synonyms: CTR9, p150, SH2BP1, SH2 domain-binding protein 1, KIAA0155, p150TSP, TSBP
Target Sequences: NM_014633 NP_055448.1 Q6PD62

Filtered By: None
Target
CTR9 (11)
Reactivity
Human (11)
Mouse (4)
Rat (3)
Bat (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Horse (4)
Monkey (4)
Orangutan (3)
Application
IHC (5)
IHC-P (3)
WB (10)
ELISA (2)
IF (4)
IP (1)
Peptide-ELISA (1)
Host
rabbit (11)
Isotype
IgG (5)
Clonality
polyclonal pc (11)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (8)
Epitope
aa1055-1104 (4)
aa1022-1056 (2)
aa1123-1173 (2)
Publications
No (11)
Showing 1-11 of 11 results

CTR9 Antibody (aa1022-1056) LS-C356324
Rabbit Polyclonal to Mouse CTR9
Mouse, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
400µl  $305.00
Immunohistochemical of paraffin-embedded M. testis section using Mouse Ctr9 antibody diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Immunohistochemical of paraffin-embedded M. colon section using Mouse Ctr9 antibody diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Immunohistochemical of paraffin-embedded M. testis section using Mouse Ctr9 antibody diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Immunohistochemical of paraffin-embedded M. colon section using Mouse Ctr9 antibody diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

CTR9 Antibody LS-C753099
Rabbit Polyclonal (IgG) to Human CTR9
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

CTR9 Antibody LS-C753098
Rabbit Polyclonal (IgG) to Human CTR9
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

CTR9 Antibody (aa1123-1173) LS-C288189
Rabbit Polyclonal (IgG) to Human CTR9
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Detection of Human CTR9 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CTR9 antibody used for IP at 6 ug/mg lysate. CTR9 was also immunoprecipitated by a previous lot of this antibody. For blotting immunoprecipitated CTR9, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Detection of Human CTR9 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CTR9 antibody used for IP at 6 ug/mg lysate. CTR9 was also immunoprecipitated by a previous lot of this antibody. For blotting immunoprecipitated CTR9, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

CTR9 Antibody (aa1123-1173) LS-C286527
Rabbit Polyclonal (IgG) to Human CTR9
Mouse, Rat, Human
IF IHC IHC-P
Unconjugated
100µl  $415.00
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:250.
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:250.
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:250.
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:250.

CTR9 Antibody LS-C332704
Rabbit Polyclonal (IgG) to Human CTR9
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cells.
Western blot analysis of extracts of various cells.

CTR9 Antibody (aa1022-1056) LS-C344436
Rabbit Polyclonal to Human CTR9
Human
WB
Unconjugated
400µl  $305.00
Western blot of lysates from A431, HT-29 cell line (from left to right) with Mouse Ctr9 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
Western blot of lysates from A431, HT-29 cell line (from left to right) with Mouse Ctr9 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

CTR9 Antibody (aa1055-1104) LS-C151791
Rabbit Polyclonal to Human CTR9
Dog, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTR9 Antibody (aa1055-1104, HRP) LS-C472388
Rabbit Polyclonal to Human CTR9
Dog, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTR9 Antibody (aa1055-1104, Biotin) LS-C472386
Rabbit Polyclonal to Human CTR9
Dog, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CTR9 Antibody (aa1055-1104, FITC) LS-C472387
Rabbit Polyclonal to Human CTR9
Dog, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-11 of 11 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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