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CTPS

CTP synthase 1

This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.

Gene Name: CTP synthase 1
Synonyms: CTPS1, CTP synthase, CTP synthetase 1, CTP synthase 1, CTPS, UTP--ammonia ligase 1
Target Sequences: NM_001905 NP_001896.2 P17812

Publications (1)

1
Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular juvenescence. Takao Morimune , Ayami Tano , Yuya Tanaka , Haruka Yukiue, Takefumi Yamamoto, Ikuo Tooyama, Yoshihiro Maruo, Masaki Nishimura, Masaki Mori. PloS one. 2021 Apr;16:e0248517. [Full Text Article] [PubMed:33886577] [PMC:PMC8062039] Related Antibodies: LS-C197001.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).