Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
CTNND2 / Delta-2 Catenin is an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | catenin (cadherin-associated protein), delta 2 |
Family/Subfamily: | Catenin , not assigned-Catenin |
Synonyms: | CTNND2, Delta-catenin, GT24, Neurojungin, NPRAP, Catenin delta-2, T-cell delta-catenin |
Target Sequences: | NM_001332 NP_001323.1 Q9UQB3 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.