CTNNB1 / Beta Catenin

catenin (cadherin-associated protein), beta 1, 88kDa

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

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Products

ELISA Kits (30)

Type

Cell-Based (1)

Cell-Based Phosphorylation (4)

Custom (3)

Development Kit (3)

Sandwich (17)

Sandwich CLIA (2)

Target

CTNNB1 / Beta Catenin (30)

Reactivity

Human (11)

Mouse (11)

Rat (10)

Chicken (1)

Dog (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit DuoPlus (3)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (8)

96-Well Strip Plate (17)

Antibody Pair and Standard (3)

Publications

No (30)

Sample Type

Adherent Cell Cultures (5)

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (13)

Serum (13)

Tissue Homogenates (8)

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Mouse CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F4891

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$818

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Human CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F4396

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Rat CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F7875

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$856

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Human CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F11242

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Mouse/Human/Rat Phospho-CTNNB1 / Beta Catenin (Tyr489) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1652

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F21325

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Human CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F20972

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F11243

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse/Human/Rat Phospho-CTNNB1 / Beta Catenin (Thr41, Ser45) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1461

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat Phospho-CTNNB1 / Beta Catenin (Ser37) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1460

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human/Rat CTNNB1 / Beta Catenin (Cell-Based ELISA) ELISA Kit - LS-F1859

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Monkey CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42050

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Porcine CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42052

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Guinea pig CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42051

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Sheep CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42053

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

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Chicken CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42047

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rabbit CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F42049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

DevKit DuoPlus Rat CTNNB1 / Beta Catenin ELISA Development Kit - LS-F72144

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,305; 1000 Wells/$1,952

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DevKit DuoPlus Human CTNNB1 / Beta Catenin ELISA Development Kit - LS-F71792

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,229; 1000 Wells/$1,826

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DevKit DuoPlus Mouse CTNNB1 / Beta Catenin ELISA Development Kit - LS-F71880

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,254; 1000 Wells/$1,867

Select

Bovine CTNNB1 / Beta Catenin (Custom ELISA) ELISA Kit - LS-F15641

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse CTNNB1 / Beta Catenin (Custom ELISA) ELISA Kit - LS-F15642

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Dog CTNNB1 / Beta Catenin (Custom ELISA) ELISA Kit - LS-F15643

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

Select

Rat CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F21507

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse CTNNB1 / Beta Catenin (Sandwich ELISA) ELISA Kit - LS-F32709

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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