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CTMP / THEM4
thioesterase superfamily member 4
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
| Gene Name: | thioesterase superfamily member 4 |
| Synonyms: | THEM4, C-terminal modulator protein, CTMP |
| Target Sequences: | NP_444283.2 Q5T1C6 |
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