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CTGF

connective tissue growth factor

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Gene Name: connective tissue growth factor
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: CTGF, CCN family member 2, CCN2, IGFBP8, IGF-binding protein 8, NOV2, HCS24, IBP-8, IGFBP-8
Target Sequences: NM_001901 NP_001892.1 P29279

Publications (5)

1
A physiological role for connective tissue growth factor in early wound healing. Alfaro MP, Deskins DL, Wallus M, DasGupta J, Davidson JM, Nanney LB, A Guney M, Gannon M, Young PP. Laboratory investigation; a journal of technical methods and pathology. 2013 93:81-95. (ICC, IHC; Mouse) [PubMed:23212098]
2
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human) [Full Text Article] [PubMed:29854742] [PMC:PMC5944282]
3
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Jack Leslie, Marina García Macia, Saimir Luli, Julie C Worrell, William J Reilly, Hannah L Paish, Amber Knox, Ben S Barksby, Lucy M Gee, Marco Y W Zaki, Amy L Collins, Rachel A Burgoyne, Rainie Cameron, Charlotte Bragg, Xin Xu, Git W Chung, Colin D A Brown, Andrew D Blanchard, Carmel B Nanthakumar, Morten Karsdal, Stuart M Robinson, Derek M Manas, Gourab Sen, Jeremy French, Steven A White, Sandra Murphy, Matthias Trost, Johannes L Zakrzewski, Ulf Klein, Robert F Schwabe, Ingmar Mederacke, Colin. Nature metabolism. 2020 November;2:1350-1367. [Full Text Article] [PubMed:33168981] [PMC:PMC7116435]
4
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797]
5
Calcineurin (PPP3CB) regulates angiotensin II-dependent vascular remodelling by potentiating EGFR signalling in mice. Alexander Nolze, Conny Köhler, Stefanie Ruhs, Katja Quarch, Nicole Strätz, Michael Gekle, Claudia Grossmann. Acta physiologica (Oxford, England). 2021 November;233:e13715. [Full Text Article] [PubMed:34228904]
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☰ Filters
Products
Proteins (23)
Over-Expression Lysate (2)
Recombinant (21)
CTGF (23)
No (23)
10His-SUMO, N-terminus (1)
6His, N-terminus (1)
Fc, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (8)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Bovine (1)
Human (14)
Mouse (4)
Pig (1)
Rat (1)
Sheep (1)
293T Cells (1)
E. coli (15)
HEK 293 Cells (1)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (7)
Low endotoxin level (7)
Biologically active (3)
CTGF Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
37.7 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His, N-Terminal
14.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His
13.2 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
E. coli
10His-SUMO, N-terminus
62.4 kD
100 µg/$500; 1 mg/$1,679; 20 µg/$364
Select
E. coli
His
15.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
11.0 kDa
5 µg/$268; 20 µg/$349
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His
27.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
62.6 kDa
10 µg/$317; 50 µg/$524
CTGF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
100 µg/$494
CTGF Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CTGF Protein - 12.5% SDS-PAGE of human CTGF stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.94 kDa
10 µg/$479; 25 µg/$670
Select
None
Biologically active
11.2 kD
20 µg/$492
CTGF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$150
CTGF Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 50 µg/$378; 20 µg/$364
Select
E. coli
97 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
10.78 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Mammalian Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.3 kDa
10 µg/$288; 50 µg/$436
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
62.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.3kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His
36.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His-T7
29.3 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His
13.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
Select
E. coli
His
27.0 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~11.3 kDa
20 µg/$395; 1 mg/$6,427
Viewing 1-23 of 23 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).