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Ctf2 / Cardiotrophin 2 is also know as Neuropoietin. The mouse Ctf2 gene is localized in tandem with the Ctf1 gene on chromosome 7. Neuropoietin is structurally and functionally related with CNTF, cardiotrophin-1, and cardiotrophin-like cytokine. High expression of Neuropoietin is observed in embryonic neuroepithelial cells. Expression is seen also in the retina and, to a lesser extent, in skeletal muscle. In vitro, Neuropoietin is a survival factor for embryonic motor neurons. It is mitogenic for neural precursor cells in the presence of EGF and bFGF.
Gene Name: | Cardiotrophin 2 |
Synonyms: | Ctf2, Neuropoietin |
Target Sequences: | Q0VB69 |
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