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CTDNEP1 / DULLARD
CTD nuclear envelope phosphatase 1
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.
| Gene Name: | CTD nuclear envelope phosphatase 1 |
| Synonyms: | CTDNEP1, DULLARD, Dullard homolog, NET56, HSA011916 |
| Target Sequences: | NM_015343 NP_056158.2 O95476 |
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