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Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Gene Name: | CTS telomere maintenance complex component 1 |
Synonyms: | CTC1, AAF-132, AAF132, C17orf68, CST complex subunit CTC1, Alpha accessory factor 132, Tmp494178, CRMCC |
Target Sequences: | Q2NKJ3 Q2NKJ3 |
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