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CST1 / Cystatin SN

cystatin SN

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid.

Gene Name: cystatin SN
Synonyms: CST1, Cystatin SN, Cystatin 1, Cystatin SA-I, Cystatin-1, Salivary cystatin-SA-1, Cystain-SA-I, Cystatin-SN
Target Sequences: NM_001898 NP_001889.2 P01037

Publications (1)

1
Expression and Functional Analysis of CST1 in Intractable Nasal Polyps. Kato Y, Takabayashi T, Sakashita M, Imoto Y, Tokunaga T, Ninomiya T, Morikawa T, Yoshida K, Noguchi E, Fujieda S. American journal of respiratory cell and molecular biology. 2018 October;59:448-457. [Full Text Article] [PubMed:29698614] Related Antibodies: LS-B5996.

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
CST1 / Cystatin SN (7)
No (7)
6His, C-terminus (2)
GST (1)
His (1)
His-S (1)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
CST1 / Cystatin SN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
16.39 kDa
100 µg/$494
CST1 / Cystatin SN Protein - 12.5% SDS-PAGE of human CST1 stained with Coomassie Blue
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Wheat Germ Extract
GST
42.8 kDa
10 µg/$479; 25 µg/$670
CST1 / Cystatin SN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.39 kDa
20 µg/$150
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.4 kDa
10 µg/$317; 50 µg/$524
CST1 / Cystatin SN Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.35kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
CST1 / Cystatin SN Protein - Recombinant Cystatin 1 By SDS-PAGE
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E. coli
His-S
20.0 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).