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CST1 / Cystatin SN

cystatin SN

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid.

Gene Name: cystatin SN
Synonyms: CST1, Cystatin SN, Cystatin 1, Cystatin SA-I, Cystatin-1, Salivary cystatin-SA-1, Cystain-SA-I, Cystatin-SN
Target Sequences: NM_001898 NP_001889.2 P01037

Publications (1)

1
Expression and Functional Analysis of CST1 in Intractable Nasal Polyps. Kato Y, Takabayashi T, Sakashita M, Imoto Y, Tokunaga T, Ninomiya T, Morikawa T, Yoshida K, Noguchi E, Fujieda S. American journal of respiratory cell and molecular biology. 2018 October;59:448-457. [Full Text Article] [PubMed:29698614] Related Antibodies: LS-B5996.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).