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CST / GAL3ST1

galactose-3-O-sulfotransferase 1

Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The CST cDNA encodes a 423-amino acid protein with a predicted type II transmembrane topology and 2 potential N-linked glycosylation sites; it is not homologous to either the cytosolic sulfotransferases or the Golgi sulfotransferases. Galactosylceramide sulfotransferase catalyzes the conversion between 3&#039-phosphoadenylylsulfate + a galactosylceramide <=> adenosine 3&#039,5&#039-bisphosphate + galactosylceramide sulfate. Activity is enhanced in renal cell carcinoma by the action of epidermal growth factor, transforming growth factor, and hepatocyte growth factor. The role of this enzyme in renal cell carcinoma is currently unknown.

Gene Name: galactose-3-O-sulfotransferase 1
Synonyms: GAL3ST1, Cerebroside sulfotransferase, CST, GalCer sulfotransferase
Target Sequences: NM_004861 NP_004852.1 Q99999

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
CST / GAL3ST1 (6)
No (6)
GST (1)
GST, N-terminus (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (4)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
CST / GAL3ST1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
48.6 kDa
100 µg/$494
CST / GAL3ST1 Protein - 12.5% SDS-PAGE of human GAL3ST1 stained with Coomassie Blue
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Wheat Germ Extract
GST
75.2 kDa
2 µg/$439
CST / GAL3ST1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CST / GAL3ST1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
48.6 kDa
20 µg/$150
CST / GAL3ST1 Protein - Recombinant Galactose-3-O-Sulfotransferase 1 By SDS-PAGE
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E. coli
His-GST
48.5 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
CST / GAL3ST1 Protein - Recombinant Galactose-3-O-Sulfotransferase 1 By SDS-PAGE
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E. coli
His-T7
28.6 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).