CSNK2A2

casein kinase 2, alpha prime polypeptide

Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV.

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Antibodies (47)

Proteins (10)

ELISA Kits (6)

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Custom (2)

Over-Expression Lysate (2)

Primary (47)

Recombinant (8)

Sandwich (4)

Target

CSNK2A2 (63)

Reactivity

Human (50)

Mouse (22)

Rat (13)

Bat (6)

Bovine (7)

Chimpanzee (6)

Dog (6)

Guinea pig (3)

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Application

IHC (15)

IHC-P (10)

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ELISA (24)

ICC (1)

IF (7)

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Host

rabbit (37)

mouse (10)

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IHCPlus (3)

Isotype

IgG (32)

IgG1 (2)

IgG2a,k (6)

IgG2b (1)

IgG2b,k (1)

Clonality

monoclonal mc (10)

polyclonal pc (37)

Clone

02 (1)

10 (2)

4F2 (1)

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96-Well Strip Plate (6)

APC Conjugated (3)

Azide-free (1)

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FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (3)

Preservative Free (2)

Unconjugated (23)

Epitope

aa4-32 (7)

C-Terminus (4)

aa251-300 (4)

Amino Acid: 194-350 (1)

aa1-100 (1)

aa300-C-term (1)

aa69-310 (1)

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No (63)

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Plasma (4)

Serum (4)

Tissue Homogenates (2)

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GST (1)

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His (2)

His-GST (1)

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Source

293T Cells (1)

Baculovirus (2)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (3)

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IHC-plus™ CSNK2A2 Antibody LS-B13833

(4.0) Rating

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CSNK2A2 Antibody (HRP) LS-C318499

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CSNK2A2 Antibody (Biotin) LS-C318495

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CSNK2A2 Antibody (FITC) LS-C318497

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CSNK2A2 Antibody (aa251-300) LS-B11950

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (aa251-300) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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CSNK2A2 Antibody (aa251-300, HRP) LS-C457801

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CSNK2A2 Antibody (aa251-300, FITC) LS-C457800

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

IHC-plus™ CSNK2A2 Antibody (aa300-C-term) LS-B11287

(4.0) Rating

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (aa300-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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CSNK2A2 Antibody (clone 10) LS-C169119

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (10) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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CSNK2A2 Antibody LS-C331589

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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CSNK2A2 Antibody (Preservative Free) LS-C817933

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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Human CSNK2A2 Protein (Recombinant His) - LS-G1916

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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CSNK2A2 Antibody LS-C748531

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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CSNK2A2 Antibody (Amino Acid: 194-350, clone 10) LS-C758462

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (Amino Acid: 194-350) (10) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µl/$503

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CSNK2A2 Antibody (clone 4F2) LS-C196986

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (4F2) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$423

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CSNK2A2 Antibody (aa69-310) LS-C178877

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal (aa69-310) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

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CSNK2A2 Antibody LS-C664830

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CSNK2A2 Antibody LS-C765834

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CSNK2A2 Antibody (aa4-32) LS-C320640

Antibody:

CSNK2A2 Rabbit anti-Mouse Polyclonal (aa4-32) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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CSNK2A2 Antibody LS-C192741

Antibody:

CSNK2A2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

CSNK2A2 Antibody (aa1-100) LS-C307109

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (aa1-100) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

CSNK2A2 Antibody (Biotin) LS-C521502

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

CSNK2A2 Antibody (FITC) LS-C531547

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

CSNK2A2 Antibody (PE) LS-C649746

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

CSNK2A2 Antibody (APC) LS-C513288

Antibody:

CSNK2A2 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• Biotin
• FITC
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC

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