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CSNK1E / CK1 Epsilon

casein kinase 1, epsilon

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.

Gene Name: casein kinase 1, epsilon
Family/Subfamily: Protein Kinase , Casein kinase I
Synonyms: CSNK1E, Casein kinase 1 epsilon, Casein kinase i epsilon, CK1 epsilon, CKIE, CKIepsilon, CKI-epsilon, HCKIE, Casein kinase 1, epsilon
Target Sequences: NM_001894 NP_001885.1 P49674

Publications (1)

1
Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells. Rodriguez N, Yang J, Hasselblatt K, Liu S, Zhou Y, Rauh-Hain JA, Ng SK, Choi PW, Fong WP, Agar NY, Welch WR, Berkowitz RS, Ng SW. EMBO molecular medicine. 2012 4:952-63. [PubMed:22707389] [PMC:PMC3491827] Related Antibodies: LS-C100599.

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Products
Proteins (12)
Over-Expression Lysate (4)
Recombinant (8)
CSNK1E / CK1 Epsilon (12)
No (12)
GST (2)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (6)
Human (10)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Insect Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
Biologically active (1)
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E. coli
His
51.4 kD
100 µg/$408; 20 µg/$311
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Yeast
His
49.3 kD
500 µg/$1,000; 100 µg/$436; 20 µg/$326
CSNK1E / CK1 Epsilon Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$469; 25 µg/$630
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E. coli
GST
51.9 kD
1 mg/$1,207; 100 µg/$408; 20 µg/$311
CSNK1E / CK1 Epsilon Protein - Purified recombinant protein CSNK1E was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$1,005
CSNK1E / CK1 Epsilon Protein - Purified recombinant protein CSNK1E was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$1,005
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Insect Cells
None
Biologically active
~72 kDa
10 µg/$481
CSNK1E / CK1 Epsilon Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
100 µg/$458
CSNK1E / CK1 Epsilon Protein - 12.5% SDS-PAGE of human CSNK1E stained with Coomassie Blue
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Wheat Germ Extract
GST
73.7 kDa
2 µg/$429
CSNK1E / CK1 Epsilon Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.1 kDa
100 µg/$458
Select
293T Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$130
CSNK1E / CK1 Epsilon Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.1 kDa
20 µg/$130
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).