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CSH1 / Placental Lactogen

chorionic somatomammotropin hormone 1 (placental lactogen)

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

Gene Name: chorionic somatomammotropin hormone 1 (placental lactogen)
Synonyms: CSH1, Choriomammotropin, Chorionic somatomammotropin A, CS-1, HCS-A, PL, Placental lactogen, Lactogen, CSA, CSMT
Target Sequences: NM_001317 NP_001308.1 P01243

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
CSH1 / Placental Lactogen (10)
No (10)
6His, C-terminus (2)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
CSH1 / Placental Lactogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$150
CSH1 / Placental Lactogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
28.6 kDa
20 µg/$150
CSH1 / Placental Lactogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.6 kDa
100 µg/$494
CSH1 / Placental Lactogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
100 µg/$494
CSH1 / Placental Lactogen Protein - 12.5% SDS-PAGE of human CSH1 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.61 kDa
10 µg/$479; 25 µg/$670
CSH1 / Placental Lactogen Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CSH1 / Placental Lactogen Protein - Purified recombinant protein CSH1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$1,107
CSH1 / Placental Lactogen Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.4 kDa
10 µg/$297; 50 µg/$460
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.35kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).