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CSF2RB / CD131
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSF2RB is a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defective CSF2RB has been reported to be associated with protein alveolar proteinosis.
| Gene Name: | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| Synonyms: | CSF2RB, CD131 antigen, CDw131, IL3RB, IL5RB, SMDP5, CD131, GM-CSF receptor beta chain |
| Target Sequences: | NM_000395 NP_000386.1 P32927 |
Publications (2)
1
Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors. Urdinguio RG, Fernandez AF, Moncada-Pazos A, Huidobro C, Rodriguez RM, Ferrero C, Martinez-Camblor P, Obaya AJ, Bernal T, Parra-Blanco A, Rodrigo L, Santacana M, Matias-Guiu X, Soldevilla B, Dominguez G, Bonilla F, Cal S, Lopez-Otin C, Fraga MF. Cancer research. 2013 73:395-405. (IHC-P; Human)
[PubMed:23108143]
Related Antibodies: LS-B6993.
2
uPA and uPAR shRNA inhibit angiogenesis via enhanced secretion of SVEGFR1 independent of GM-CSF but dependent on TIMP-1 in endothelial and glioblastoma cells. Hari Raghu, Arun Kumar Nalla, Christopher S Gondi, Meena Gujrati, Dzunh H Dinh, Jasti S Rao. Molecular oncology. 2012 February;6:33-47. [Full Text Article]
[PubMed:22177802]
[PMC:PMC3268919]
Related Antibodies: LS-C96892.
☰ Filters
Products
Proteins
(6)
Type
Over-Expression Lysate
(2)
Recombinant
(4)
Target
CSF2RB / CD131
(6)
Application
Bind
(1)
ELISA
(1)
Func
(1)
SDS-PAGE
(1)
Publications
No
(6)
Tag
His
(1)
His,C-terminus
(1)
His-GST
(1)
Myc-DDK (Flag)
(3)
Species
Human
(5)
Source
293T Cells
(1)
E. coli
(1)
HEK 293 Cells
(3)
Human Cells
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(2)
Biologically Active
Biologically active
(1)
HEK 293 Cells
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CSF2RB consists of 438 amino acids and has a predicted molecular mass of 50 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CSF2RB is approximately 50-55 kDa.
100 µg/$441; 1 mg/$2,003
HEK 293 Cells
Myc-DDK (Flag)
97.34 kDa
100 µg/$710
293T Cells
Myc-DDK (Flag)
97.34 kDa
20 µg/$215
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
50 kDa
100 µg/$721
HEK 293 Cells
Myc-DDK (Flag)
95.7 kDa
20 µg/$1,107
E. coli
His-GST
38.3 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
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