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CSF2RA / CD116

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

CSF2RA / CD116 is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.

Gene Name: colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Synonyms: CSF2RA, CD116, CD116 antigen, CDw116, CSF2R, CSF2RX, CSF2RY, CSF2RAY, GM-CSF-R-alpha, GM-CSF receptor alpha subunit, GMCSFR, GMR, GMR-alpha, SMDP4, CSF2RAX, GMCSFR-alpha, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Target Sequences: NP_006131.2 P15509

Publications (1)

1
Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis. Greven DE, Cohen ES, Gerlag DM, Campbell J, Woods J, Davis N, van Nieuwenhuijze A, Lewis A, Heasmen S, McCourt M, Corkill D, Dodd A, Elvin J, Statache G, Wicks IP, Anderson IK, Nash A, Sleeman MA, Tak PP. Annals of the rheumatic diseases. 2015 74:1924-30. (WB; Human) [Full Text Article] [PubMed:24936585] [PMC:PMC4602263] Related Antibodies: LS-C40980.

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Products
Proteins (24)
Over-Expression Lysate (10)
Recombinant (14)
CSF2RA / CD116 (24)
No (24)
6His, C-terminus (3)
Fc, C-terminus (1)
GST (1)
His (2)
His,N-terminus + GST (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (14)
Human (18)
Mouse (1)
293T Cells (5)
E. coli (5)
HEK 293 Cells (10)
Human Cells (1)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (4)
Biologically active (1)
CSF2RA / CD116 Protein - Recombinant Colony Stimulating Factor 2 Receptor Alpha By SDS-PAGE
Select
E. coli
His,N-terminus + GST
18.6 kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 1 mg/$1,723; 5 mg/$2,673; 2 mg/$1,900
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.5kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627
CSF2RA / CD116 Protein - Purified recombinant protein CSF2RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
44.1 kDa
20 µg/$1,107
CSF2RA / CD116 Protein - Purified recombinant protein CSF2RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
44.1 kDa
20 µg/$1,107
CSF2RA / CD116 Protein - Purified recombinant protein CSF2RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
44.1 kDa
20 µg/$1,107
CSF2RA / CD116 Protein - Purified recombinant protein CSF2RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$1,107
CSF2RA / CD116 Protein - Recombinant Colony Stimulating Factor 2 Receptor Alpha By SDS-PAGE
Select
E. coli
His
19.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CSF2RA / CD116 Protein - Recombinant Colony Stimulating Factor 2 Receptor Alpha By SDS-PAGE
Select
E. coli
His-GST
42.3 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CSF2RA / CD116 Protein
Select
E. coli
His-SUMO
50.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CSF2RA / CD116 Protein - 12.5% SDS-PAGE of human CSF2RA stained with Coomassie Blue
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Wheat Germ Extract
GST
69.74 kDa
10 µg/$479; 25 µg/$670
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
100 µg/$494
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
44.1 kDa
100 µg/$494
CSF2RA / CD116 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
35.5 kDa
50 µg/$453; 10 µg/$298; 1 mg/$2,064; 500 µg/$1,470
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.9 kDa
100 µg/$494
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.21 kDa
100 µg/$494
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.21 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.5 kDa
10 µg/$277; 50 µg/$389
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.2 kDa
100 µg/$721
CSF2RA / CD116 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.21 kDa
20 µg/$150
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.9 kDa
20 µg/$150
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.21 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
44.1 kDa
20 µg/$150
CSF2RA / CD116 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$150
Viewing 1-24 of 24 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).