CS1 / CLSTN1

calsyntenin 1

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.

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Products

Antibodies (25)

Proteins (6)

ELISA Kits (2)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (25)

Recombinant (4)

Sandwich (1)

Target

CS1 / CLSTN1 (33)

Reactivity

Human (27)

Mouse (5)

Rat (4)

Bat (3)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

Zebrafish (3)

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Application

IHC (8)

IHC-P (6)

WB (22)

ELISA (10)

Peptide-ELISA (1)

Host

rabbit (25)

Product Group

IHCPlus (1)

Isotype

IgG (16)

Clonality

polyclonal pc (25)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Preservative Free (1)

Unconjugated (12)

Epitope

aa15-42 (7)

aa35-84 (4)

C-Terminus (2)

Publications

No (33)

Sample Type

Plasma (1)

Serum (1)

Tag

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (1)

Select

CS1 / CLSTN1 Antibody (aa35-84) LS-B9743

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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CS1 / CLSTN1 Antibody (aa35-84, HRP) LS-C446760

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody

Reactivity:

Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CS1 / CLSTN1 Antibody (aa35-84, Biotin) LS-C446757

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody

Reactivity:

Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CS1 / CLSTN1 Antibody (aa35-84, FITC) LS-C446758

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody

Reactivity:

Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CS1 / CLSTN1 Antibody (C-Terminus) LS-C153284

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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Human CS1 / CLSTN1 (Sandwich ELISA) ELISA Kit - LS-F38084

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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CS1 / CLSTN1 Antibody LS-C483890

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

CS1 / CLSTN1 Antibody LS-C806978

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CS1 / CLSTN1 Antibody (C-Terminus) LS-C144685

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

Select

CS1 / CLSTN1 Antibody LS-C664656

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

CS1 / CLSTN1 Antibody (aa15-42) LS-C320461

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CS1 / CLSTN1 Antibody (aa15-42, Biotin) LS-C233987

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CS1 / CLSTN1 Antibody (aa15-42, FITC) LS-C233988

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CS1 / CLSTN1 Antibody (aa15-42, APC) LS-C233986

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CS1 / CLSTN1 Antibody (aa15-42, PE) LS-C233990

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

CS1 / CLSTN1 Antibody (aa15-42, Azide-free, HRP) LS-C249705

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

CS1 / CLSTN1 Antibody LS-C483891

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

CS1 / CLSTN1 Antibody LS-C309937

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

CS1 / CLSTN1 Antibody (HRP) LS-C541519

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

CS1 / CLSTN1 Antibody (Biotin) LS-C521387

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

CS1 / CLSTN1 Antibody (FITC) LS-C531430

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

CS1 / CLSTN1 Antibody (APC) LS-C513172

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC

Select

CS1 / CLSTN1 Antibody (aa15-42) LS-C159372

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (aa15-42) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

CS1 / CLSTN1 Antibody LS-C750374

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CS1 / CLSTN1 Antibody (Preservative Free) LS-C814779

Antibody:

CS1 / CLSTN1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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