CRYAA / Alpha A Crystallin

crystallin, alpha A

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).

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ELISA Kits (8)

Type

Custom (7)

Sandwich (1)

Target

CRYAA / Alpha A Crystallin (8)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Chicken (1)

Dog (1)

Pig (1)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

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Mouse CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17344

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17345

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Rat CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17346

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Dog CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17339

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Pig CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17341

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17342

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken CRYAA / Alpha A Crystallin (Custom ELISA) ELISA Kit - LS-F17343

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human CRYAA / Alpha A Crystallin (Sandwich ELISA) ELISA Kit - LS-F35382

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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