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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CRY1

cryptochrome circadian clock 1

CRY1 / Cryptochrome circadian clock 1 encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

Gene Name: cryptochrome circadian clock 1
Synonyms: CRY1, Chryptochrome 1, Cryptochrome-1, Photolyase homolog 1, PHLL1
Target Sequences: NM_004075 NP_004066.1 Q16526

Filtered By: None
Target
CRY1 (41)
Reactivity
Human (38)
Mouse (11)
Rat (8)
Bat (4)
Bovine (5)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (5)
Monkey (4)
Pig (5)
Sheep (5)
Application
IHC (28)
IHC-Fr (1)
IHC-P (7)
WB (39)
DB (2)
ELISA (13)
ICC (2)
IF (3)
IP (3)
Host
rabbit (35)
mouse (5)
goat (1)
Isotype
IgG (29)
IgG1 (3)
IgG1,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (37)
Clone
3551C4a (2)
4H4-1C4 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (23)
Epitope
aa3-132 (10)
aa556-586 (8)
aa151-200 (4)
C-Terminus (3)
aa115-224 (1)
aa153-189 (1)
aa507-586 (1)
aa536-586 (1)
aa551-555 (1)
Publications
No (41)
Showing 1-25 of 41 results

CRY1 Antibody (clone 4H4-1C4) IHC-plus™ LS-B5393
Mouse Monoclonal [clone 4H4-1C4] (IgG1,k) to Human CRY1
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 0.33mg/ml  $485.00
Anti-CRY1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Immunofluorescence of monoclonal antibody to CRY1 on HeLa cell. [antibody concentration 10 ug/ml]
Anti-CRY1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Immunofluorescence of monoclonal antibody to CRY1 on HeLa cell. [antibody concentration 10 ug/ml]

CRY1 Antibody (C-Terminus) LS-C6227
Rabbit Polyclonal (IgG) to Mouse CRY1
Mouse
ELISA IHC IHC-Fr IP WB
Unconjugated
100µg 100µl 1mg/ml  $755.00

CRY1 Antibody (C-Terminus) LS-C6226
Rabbit Polyclonal (IgG) to Mouse CRY1
Mouse
ELISA IP WB
Unconjugated
100µl  $725.00

CRY1 Antibody (aa115-224) LS-C36021
Goat Polyclonal (IgG) to Human CRY1
Mouse, Human
ELISA IHC WB
Unconjugated
100µg 500µl 0.2mg/ml  $770.00

CRY1 Antibody (aa151-200) IHC-plus™ LS-B6955
Rabbit Polyclonal to Human CRY1
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CRY1 Antibody (aa151-200, HRP) LS-C466704
Rabbit Polyclonal to Human CRY1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CRY1 Antibody (aa151-200, Biotin) LS-C466702
Rabbit Polyclonal to Human CRY1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CRY1 Antibody (aa151-200, FITC) LS-C466703
Rabbit Polyclonal to Human CRY1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CRY1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

CRY1 Antibody LS-C753110
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IF IHC WB
Unconjugated
100µg  $335.00

CRY1 Antibody (aa556-586) LS-C327130
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
Unconjugated
200µl 0.25mg/ml  $530.00

CRY1 Antibody (aa556-586, Biotin) LS-C276513
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

CRY1 Antibody (aa556-586, FITC) LS-C276514
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

CRY1 Antibody (aa556-586, AP) LS-C276511
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

CRY1 Antibody (aa556-586, APC) LS-C276512
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

CRY1 Antibody (aa556-586, Azide-free, HRP) LS-C276515
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

CRY1 Antibody (aa556-586, PE) LS-C276516
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

CRY1 Antibody (aa507-586) LS-C377533
Rabbit Polyclonal (IgG) to Human CRY1
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1:100 dilution.

CRY1 Antibody (aa556-586) LS-C100382
Rabbit Polyclonal to Human CRY1
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-Cry1 N-term antibody is used in Western blot to detect Cry1 in placenta tissue lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-Cry1 N-term antibody is used in Western blot to detect Cry1 in placenta tissue lysate.

CRY1 Antibody LS-C355593
Rabbit Polyclonal (IgG) to Human CRY1
Human
IF WB
Unconjugated
100µg  $425.00
Immunofluorescence analysis of Cryptochrome 1 was performed using 70% confluent log phase U-87 MG cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cryptochrome 1 Rabbit Polyclonal Antibody at 2µg/ml in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, Alexa Fluor® 488 conjµgate at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Alexa Fluor® 555 Rhodamine Phalloidin. Panel d represents the merged image showing cytoplasmic localization. Panel e shows the no primary antibody control. The images were captured at 60X magnification.
Immunofluorescence analysis of Cryptochrome 1 was performed using 70% confluent log phase U-87 MG cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cryptochrome 1 Rabbit Polyclonal Antibody at 2µg/ml in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, Alexa Fluor® 488 conjµgate at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Alexa Fluor® 555 Rhodamine Phalloidin. Panel d represents the merged image showing cytoplasmic localization. Panel e shows the no primary antibody control. The images were captured at 60X magnification.

CRY1 Antibody LS-C412580
Rabbit Polyclonal to Human CRY1
Human
IHC WB
Unconjugated
100µl  $385.00

CRY1 Antibody (aa3-132) LS-C372959
Rabbit Polyclonal (IgG) to Human CRY1
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of CRY1 antibody.
Western blot of CRY1 antibody.

CRY1 Antibody (aa3-132, FITC) LS-C422094
Rabbit Polyclonal (IgG) to Human CRY1
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

CRY1 Antibody LS-C748704
Rabbit Polyclonal (IgG) to Human CRY1
Mouse, Human
IHC WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of NCI-H460 cells, using CRY1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of NCI-H460 cells, using CRY1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.

CRY1 Antibody LS-C348980
Rabbit Polyclonal (IgG) to Human CRY1
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded mouse kidney tissue.
Western blot analysis of extracts of NCI-H460 cell lines.
Immunohistochemistry of paraffin-embedded mouse kidney tissue.
Western blot analysis of extracts of NCI-H460 cell lines.

CRY1 Antibody (clone 3551C4a) LS-C342789
Mouse Monoclonal [clone 3551C4a] (IgG1) to Human CRY1
Human
DB WB
Unconjugated
100µg 0.1mg/ml  $375.00
Western blot analysis of immunized recombinant protein, using anti-CRY1 monoclonal antibody.
Western blot analysis of immunized recombinant protein, using anti-CRY1 monoclonal antibody.
Showing 1-25 of 41 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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