CRK

v-crk avian sarcoma virus CT10 oncogene homolog

CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

CRK (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human CRK Protein (Recombinant GST, N-terminus) (aa127-226) - LS-G58213

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CRK Protein (Recombinant His, N-Terminal) (Ala2-Ser304) - LS-G96907

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

36 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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Human CRK Protein (Recombinant GST) (Full Length) - LS-G28030

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

49.3 kDa

Price:

10 µg/$479; 25 µg/$670

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CRK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116106

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.7 kDa

Price:

100 µg/$494

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Human CRK Protein (Recombinant His) - LS-G989

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739

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Human CRK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78424

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.7 kDa

Price:

20 µg/$150

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Human CRK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78425

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.7 kDa

Price:

20 µg/$150

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CRK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101464

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.7 kDa

Price:

100 µg/$494

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