CRK

v-crk avian sarcoma virus CT10 oncogene homolog

CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

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Products

Antibodies (58)

Proteins (8)

ELISA Kits (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (3)

Over-Expression Lysate (4)

Primary (58)

Recombinant (4)

Sandwich (2)

Target

CRK (73)

Reactivity

Human (61)

Mouse (32)

Rat (24)

Bat (3)

Bovine (3)

Chicken (1)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Hamster (4)

Horse (3)

Monkey (7)

Rabbit (4)

Xenopus (3)

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Application

IHC (17)

IHC-P (3)

WB (45)

Flo (5)

DB (9)

ELISA (19)

ICC (6)

IF (19)

Peptide-ELISA (4)

Host

rabbit (44)

mouse (14)

Isotype

IgG (30)

IgG1 (3)

IgG2b (7)

Clonality

monoclonal mc (13)

polyclonal pc (45)

Clone

1D4B (1)

2210C1a (2)

3G11C1 (2)

3G11E8 (2)

Format

96-Well Microplate (2)

96-Well Strip Plate (5)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (42)

Epitope

pSer41 (7)

pTyr221 (7)

aa182-231 (4)

160-240 aa (2)

aa1-204 (2)

Internal (1)

aa187-236 (1)

aa2-246 (1)

aa200-250 (1)

aa205-304 (1)

p221 (1)

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Publications

No (73)

Sample Type

Adherent Cell Cultures (2)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

CRK Antibody (aa200-250) LS-C175979

Antibody:

CRK Rabbit anti-Human Polyclonal (aa200-250) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CRK Antibody (phospho-Tyr221) LS-C825828

Antibody:

CRK Rabbit anti-Human Polyclonal (pTyr221) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CRK Antibody (clone 3G11E8) LS-C758675

Antibody:

CRK Mouse anti-Human Monoclonal (3G11E8) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$518

Select

CRK Antibody (clone 3G11C1) LS-C758963

Antibody:

CRK Mouse anti-Human Monoclonal (3G11C1) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

Select

CRK Antibody (clone 3G11E8) LS-C169407

Antibody:

CRK Mouse anti-Human Monoclonal (3G11E8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

CRK Antibody (clone 3G11C1) LS-C169406

Antibody:

CRK Mouse anti-Human Monoclonal (3G11C1) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

CRK Antibody LS-C814011

Antibody:

CRK Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

CRK Antibody (p221) LS-C825829

Antibody:

CRK Rabbit anti-Human Polyclonal (p221) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CRK Antibody LS-C417542

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

CRK Antibody (aa187-236) LS-C117559

Antibody:

CRK Rabbit anti-Human Polyclonal (aa187-236) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CRK Antibody LS-C808656

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CRK Antibody (160-240 aa) LS-C382897

Antibody:

CRK Rabbit anti-Human Polyclonal (160-240 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CRK Antibody LS-C109329

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

CRK Antibody (aa2-246) LS-C343963

Antibody:

CRK Rabbit anti-Human Polyclonal (aa2-246) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CRK Antibody (phospho-Tyr221) LS-C808519

Antibody:

CRK Rabbit anti-Human Polyclonal (pTyr221) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CRK Antibody (phospho-Tyr221) LS-C416697

Antibody:

CRK Rabbit anti-Human Polyclonal (pTyr221) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

CRK Antibody LS-C761114

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

Select

CRK Antibody (160-240 aa) LS-C381120

Antibody:

CRK Rabbit anti-Human Polyclonal (160-240 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CRK Antibody LS-C671036

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CRK Antibody (phospho-Tyr221) LS-C198841

Antibody:

CRK Rabbit anti-Human Polyclonal (pTyr221) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CRK Antibody (Internal) LS-C353943

Antibody:

CRK Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

CRK Antibody LS-C765798

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CRK Antibody LS-C404842

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CRK Antibody LS-C401551

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CRK Antibody LS-C348940

Antibody:

CRK Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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