Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
CREBL1 / ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | activating transcription factor 6 beta |
Synonyms: | ATF6B, ATF6-beta, Creb-related protein, CREBL1, G13, CREB-RP, Protein G13 |
Target Sequences: | NM_004381 NP_004372.3 Q99941 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.