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CRAT

carnitine O-acetyltransferase

Carnithine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs is thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The sequence within this record contains 5' mitochondrial sequences and represents the splice variant that localizes to the mitochondria.

Gene Name: carnitine O-acetyltransferase
Synonyms: CRAT, CAT1, Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase
Target Sequences: NM_004003 NP_003994.2 P43155

Publications (1)

1
Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Beckmann J, Schubert J, Morhenn HG, Grau V, Schnettler R, Lips KS. Cell and tissue research. 2015 359:465-477. (WB; Human) [Full Text Article] [PubMed:25418136] [PMC:PMC4320306] Related Antibodies: LS-C167021.

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
CRAT (11)
No (11)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7 (3)
Myc-DDK (Flag) (5)
Human (7)
Mouse (1)
Rat (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
CRAT Protein - Purified recombinant protein CRAT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
68.4 kDa
20 µg/$1,107
CRAT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CRAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68.4 kDa
20 µg/$215
CRAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
70.87 kDa
20 µg/$215
CRAT Protein
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E. coli
His, N-Terminal
69.6 kDa
50 µg/$419
CRAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.87 kDa
100 µg/$710
CRAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68.4 kDa
100 µg/$710
CRAT Protein - Recombinant  Carnitine Acetyltransferase By SDS-PAGE
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E. coli
His-T7
33.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CRAT Protein - Recombinant  Carnitine Acetyltransferase By SDS-PAGE
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E. coli
His-T7
52.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CRAT Protein - Recombinant  Carnitine Acetyltransferase By SDS-PAGE
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E. coli
His-T7
27.0 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
CRAT Protein - 12.5% SDS-PAGE of human CRAT stained with Coomassie Blue
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Wheat Germ Extract
GST
97.3 kDa
2 µg/$439
Viewing 1-11 of 11 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).