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CPN1

carboxypeptidase N, polypeptide 1

Carboxypeptidase N (CPN)is a plasma metallo-protease that cleaves basic amino acid residues from the C terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex with a molecular weight of 280-kD consisting of two identical small enzymatically active (catalytic) subunits of 50-kD (this record) and two large 83-kD regulatory subunits. The gene that encodes the 50-kD catalytic subunit has been mapped to chromosome 10 but its exact location is unknown.

Gene Name: carboxypeptidase N, polypeptide 1
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPN1, ACBP, Arginine carboxypeptidase, Anaphylatoxin inactivator, Carboxypeptidase K, Kininase-1, Lysine carboxypeptidase, Kininase I, Serum carboxypeptidase N, SCPN, Plasma carboxypeptidase B, CPN
Target Sequences: NM_001308 NP_001299.1 P15169

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Products
Antibodies (40)
Primary (40)
CPN1 (40)
Human (32)
Mouse (18)
Rat (16)
Bat (3)
Bovine (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (3)
Pig (6)
Rabbit (6)
Zebrafish (3)
IHC (9)
IHC-P (8)
WB (39)
Flo (2)
ELISA (6)
ICC (1)
IF (2)
Peptide-ELISA (2)
rabbit (40)
Product Group
IHCPlus (2)
IgG (12)
monoclonal mc (1)
polyclonal pc (39)
EPR6229 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (18)
aa159-325 (11)
aa221-449 (8)
aa251-300 (4)
aa323-372 (4)
380-460 aa, C-terminal (1)
C-Terminus (1)
Internal (1)
aa210-240 (1)
aa409-458 (1)
aa52-81 (1)
No (40)
CPN1 Antibody - Anti-CPN1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPN1 Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CPN1 Antibody - Anti-CPN1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPN1 Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CPN1 Antibody - Anti-CPN1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPN1 Rabbit anti-Human Polyclonal (aa251-300) (Biotin) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CPN1 Antibody - Anti-CPN1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPN1 Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CPN1 Antibody - Anti-CPN1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CPN1 Rabbit anti-Human Monoclonal (Internal) (EPR6229) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CPN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$394
CPN1 Antibody - CPN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CPN1 Rabbit anti-Human Polyclonal (aa210-240) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CPN1 Antibody - Western Blot; Sample: Recombinant CPN1, Mouse.
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CPN1 Rabbit anti-Mouse Polyclonal (aa221-449) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CPN1 Antibody - Western Blot; Sample: Recombinant CPN1, Mouse.
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CPN1 Rabbit anti-Mouse Polyclonal (aa221-449) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CPN1 Antibody - Western Blot; Sample: Recombinant CPN1, Mouse.
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CPN1 Rabbit anti-Mouse Polyclonal (aa221-449) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
CPN1 Antibody - Western Blot; Sample: Recombinant CPN1, Mouse.
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CPN1 Rabbit anti-Mouse Polyclonal (aa221-449) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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CPN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
CPN1 Antibody - Western blot of CPN1 antibody in K562, CEM, HEpG2 cell line lysates and mouse liver tissue lysates (35 ug/lane). CPN1(arrow) was detected using the purified antibody.
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CPN1 Rabbit anti-Human Polyclonal (aa52-81) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
CPN1 Antibody - Western Blot; Sample: Recombinant protein.
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CPN1 Rabbit anti-Human Polyclonal (aa159-325) Antibody
Rat, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CPN1 Antibody - Western Blot; Sample: Recombinant protein.
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CPN1 Rabbit anti-Human Polyclonal (aa159-325) (Biotin) Antibody
Rat, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
CPN1 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
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CPN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CPN1 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
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CPN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CPN1 Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CPN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CPN1 Antibody - Western blot analysis of extracts from RAW264.7 cells, using CPN1 antibody.
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CPN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CPN1 Antibody - Western blot of CPN cat antibody
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CPN1 Rabbit anti-Human Polyclonal (380-460 aa, C-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CPN1 Antibody - Western blot analysis of lysates from RAW264.7 cells, using CPN1 Antibody. The lane on the right is blocked with the synthesized peptide.
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CPN1 Rabbit anti-Human Polyclonal (aa409-458) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CPN1 Rabbit anti-Human Polyclonal (aa159-325) Antibody
Human
WB
Unconjugated
100 µl/$309
CPN1 Antibody - CPN1 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPN1 Rabbit anti-Human Polyclonal (aa323-372) Antibody
Human
WB
Unconjugated
100 µl/$424
CPN1 Antibody - Western blot analysis of Carboxypeptidase N 1 expression in HepG2 (A); HEK293T (B) whole cell lysates.
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CPN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$299
CPN1 Antibody - Western blot analysis of extracts of various cells.
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CPN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 40 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).