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CPEB1 / CPEB

cytoplasmic polyadenylation element binding protein 1

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

Gene Name: cytoplasmic polyadenylation element binding protein 1
Synonyms: CPEB1, CPE-BP1, CPE-binding protein 1, H-CEBP, HCPEB-1, CEBP, CPEB
Target Sequences: NM_030594 NP_085097.3 Q9BZB8

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Products
Proteins (16)
Over-Expression Lysate (8)
Recombinant (8)
CPEB1 / CPEB (16)
No (16)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (10)
Human (12)
293T Cells (4)
E. coli (4)
HEK 293 Cells (6)
Wheat Germ Extract (2)
Purified (2)
CPEB1 / CPEB Protein - 12.5% SDS-PAGE of human CPEB1 stained with Coomassie Blue
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Wheat Germ Extract
GST
80 kDa
2 µg/$439
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
54 kDa
20 µg/$215
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.5 kDa
20 µg/$215
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
61.9 kDa
20 µg/$150
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.5 kDa
20 µg/$150
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
61.9 kDa
100 µg/$494
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53.5 kDa
100 µg/$710
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
54 kDa
100 µg/$710
CPEB1 / CPEB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.5 kDa
100 µg/$494
CPEB1 / CPEB Protein
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E. coli
GST, N-terminus + His, C-terminus
89.9 kDa
50 µg/$419
CPEB1 / CPEB Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CPEB1 / CPEB Protein
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E. coli
His-SUMO
69.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CPEB1 / CPEB Protein - Recombinant Cytoplasmic Polyadenylation Element Binding Protein 1 By SDS-PAGE
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E. coli
His-T7
32.2 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
CPEB1 / CPEB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CPEB1 / CPEB Protein - Purified recombinant protein CPEB1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.5 kDa
20 µg/$1,107
CPEB1 / CPEB Protein - Purified recombinant protein CPEB1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.5 kDa
20 µg/$1,107
Viewing 1-16 of 16 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).