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CPE / Carboxypeptidase E

carboxypeptidase E

Carboxypeptidase E / CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Gene Name: carboxypeptidase E
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPE, Carboxypeptidase E, CPH, Carboxypeptidase H, Enkephalin convertase
Target Sequences: NM_001873 NP_001864.1 P16870

Publications (1)

1
Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content. Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2015 63:350-66. (WB; Human) [Full Text Article] [PubMed:25673289] [PMC:PMC4409946] Related Antibodies: LS-B6638.

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Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
CPE / Carboxypeptidase E (11)
No (11)
6His, C-terminus (2)
Fc (1)
GST, N-terminus (1)
His (3)
His-GST (1)
Myc-DDK (Flag) (3)
Human (10)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Human Cells (3)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (4)
CPE / Carboxypeptidase E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.15 kDa
20 µg/$130
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
49.4 kDa
10 µg/$420; 20 µg/$566
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
74.6 kDa
10 µg/$420; 20 µg/$566
CPE / Carboxypeptidase E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.15 kDa
100 µg/$458
CPE / Carboxypeptidase E Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$461; 25 µg/$611
CPE / Carboxypeptidase E Protein - Purified recombinant protein CPE was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
50.8 kDa
20 µg/$552
CPE / Carboxypeptidase E Protein
Select
E. coli
His
100 µg/$351; 500 µg/$694
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
47.1 kDa
10 µg/$397; 50 µg/$616
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
47.1kD
10 µg/$306; 50 µg/$509; 500 µg/$1,570; 1 mg/$2,242
CPE / Carboxypeptidase E Protein - Recombinant Carboxypeptidase E By SDS-PAGE
Select
E. coli
His-GST
50.8 kDa
10 µg/$278; 50 µg/$460; 100 µg/$734; 200 µg/$917; 1 mg/$2,013
CPE / Carboxypeptidase E Protein - Recombinant Carboxypeptidase E By SDS-PAGE
Select
E. coli
His
19.7 kDa
10 µg/$278; 50 µg/$460; 100 µg/$734; 200 µg/$917; 1 mg/$2,013
Viewing 1-11 of 11 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).