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CPE / Carboxypeptidase E

carboxypeptidase E

Carboxypeptidase E / CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Gene Name: carboxypeptidase E
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPE, Carboxypeptidase E, CPH, Carboxypeptidase H, Enkephalin convertase
Target Sequences: NM_001873 NP_001864.1 P16870

Publications (1)

1
Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content. Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2015 63:350-66. (WB; Human) [Full Text Article] [PubMed:25673289] [PMC:PMC4409946] Related Antibodies: LS-B6638.

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Antibodies (45)
ELISA Kits (15)
Proteins (11)
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Over-Expression Lysate (2)
Primary (45)
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CPE / Carboxypeptidase E (71)
Human (52)
Mouse (20)
Rat (17)
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rabbit (43)
mouse (1)
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Unconjugated (25)
aa151-317 (8)
aa318-476 (8)
aa36-85 (4)
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aa42-453 (2)
240-320 aa, Internal (1)
421-470 aa, C-terminal (1)
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CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) Antibody
Xenopus, Zebrafish, Rat, Bat, Rabbit, Mouse, Guinea pig, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-CPE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Xenopus, Zebrafish, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CPE / Carboxypeptidase E Antibody - Anti-Carboxypeptidase E / CPE antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$485
CPE / Carboxypeptidase E Antibody - Anti-Carboxypeptidase E / CPE antibody IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa271-320) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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CPE / Carboxypeptidase E Goat anti-Human Polyclonal (aa42-453) Antibody
Human
ELISA, Flo, IP, WB
Unconjugated
100 µg/$818
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CPE / Carboxypeptidase E Mouse anti-Human Monoclonal (aa42-453) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$771
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody in mouse cerebellum tissue lysates (35 ug/lane). CPE (arrow) was detected using the purified antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa381-412) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$386
CPE / Carboxypeptidase E Antibody - Western blot of recombinant Carboxypeptidase E / CPE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa318-476) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596
CPE / Carboxypeptidase E Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$263; 50 µl/$301; 100 µl/$359; 200 µl/$473
CPE / Carboxypeptidase E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$821
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Human, Monkey
IHC, IHC-Fr, IP, WB
Unconjugated
100 µl/$788
CPE / Carboxypeptidase E Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$385
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$292; 120 µl/$355; 200 µl/$463
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (421-470 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
CPE / Carboxypeptidase E Antibody - Positive Western Blot detected in A375 whole cell lysate. All lanes: CPE antibody at 2.7 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 54, 50 KDa. Observed band size: 54 KDa
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CPE / Carboxypeptidase E Antibody - Western blot analysis of lysate from mouse brain cells, using CPE Antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$328; 100 µg/$388
CPE / Carboxypeptidase E Antibody - Western blot analysis of extracts from 3T3 cells and RAW264.7cells, using CPE antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CPE / Carboxypeptidase E Antibody - Western blot of CPE antibody
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (240-320 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
CPE / Carboxypeptidase E Antibody - Western blot analysis of the lysates from HeLa cells using CPE antibody.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (aa256-305) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$328; 100 µl/$388
CPE / Carboxypeptidase E Antibody - Anti-CPE rabbit polyclonal antibody at 1:500 dilution. Lane A: NIH3T3 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 53 kDa. Observed band size: 53 kDa.
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IHC-P, WB
Unconjugated, Preservative Free
50 µl/$285; 100 µl/$322; 200 µl/$360
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CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$285; 200 µl/$322; 400 µl/$360
Select
CPE / Carboxypeptidase E Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µl/$300; 100 µl/$360
Viewing 1-25 of 71 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).