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CPA3

carboxypeptidase A3 (mast cell)

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A3 form, is obtained as a binary complex of a procarboxypeptidase A with a proproteinase E. Mast cell carboxypeptidase A is a secretory granule metalloexopeptidase that has a pH optimum in the neutral to basic range. It resembles pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues.

Gene Name: carboxypeptidase A3 (mast cell)
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPA3, Carboxypeptidase A3, Mast cell carboxypeptidase A, MC-CPA, Tissue carboxypeptidase A
Target Sequences: NM_001870 NP_001861.2 P15088

Publications (2)

1
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody. Simon Gebremeskel, Julia Schanin, Krysta M Coyle, Melina Butuci, Thuy Luu, Emily C Brock, Alan Xu, Alan Wong, John Leung, Wouter Korver, Ryan D Morin, Robert P Schleimer, Bruce S Bochner, Bradford A Youngblood. Frontiers in immunology. 2021 March;12:650331. [Full Text Article] [PubMed:33777047] [PMC:PMC7988091]
2
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation. Olga Krysko, Joshua H Bourne, Elena Kondakova, Elena A Galova, Katharine Whitworth, Maddy L Newby, Claus Bachert, Harriet Hill, Max Crispin, Zania Stamataki, Adam F Cunningham, Matthew Pugh, Abdullah O Khan, Julie Rayes, Maria Vedunova, Dmitri V Krysko, Alexander Brill. Frontiers in immunology. 2022 October;13:968981. [Full Text Article] [PubMed:36225927] [PMC:PMC9548604]

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CPA3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
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1 Plate/$834
CPA3 ELISA Kit
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96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$1,041
CPA3 ELISA Kit
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96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CPA3 ELISA Kit
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96-Well Strip Plate
Mouse
0.625 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$783
CPA3 ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
CPA3 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
CPA3 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
CPA3 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$893
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).