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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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COX10

cytochrome c oxidase assembly homolog 10 (yeast)

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.

Gene Name: cytochrome c oxidase assembly homolog 10 (yeast)
Synonyms: COX10, Cytochrome c oxidase subunit X, Heme O synthase, Heme A: farnesyltransferase
Target Sequences: NM_001303 NP_001294.2 Q12887

Filtered By: None
Target
COX10 (33)
Reactivity
Human (33)
Mouse (11)
Rat (10)
Bat (8)
Bovine (8)
Chicken (8)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Guinea pig (8)
Horse (8)
Monkey (8)
Orangutan (6)
Rabbit (8)
Xenopus (8)
Zebrafish (4)
Application
IHC (13)
IHC-P (3)
WB (31)
Flo (8)
ELISA (12)
IP (1)
Peptide-ELISA (1)
Host
rabbit (32)
mouse (1)
Isotype
IgG (26)
Clonality
polyclonal pc (33)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (15)
Epitope
aa383-410 (8)
aa180-229 (4)
aa215-264 (4)
Internal (2)
aa98-147 (1)
Publications
No (33)
Showing 1-25 of 33 results

COX10 Antibody (aa383-410) LS-C166961
Rabbit Polyclonal to Human COX10
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
COX10 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
COX10 Antibody western blot of CEM cell line lysates (35 ug/lane). The COX10 antibody detected the COX10 protein (arrow).
COX10 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
COX10 Antibody western blot of CEM cell line lysates (35 ug/lane). The COX10 antibody detected the COX10 protein (arrow).

COX10 Antibody (aa383-410) LS-C320540
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

COX10 Antibody (aa383-410, Biotin) LS-C221880
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

COX10 Antibody (aa383-410, FITC) LS-C221881
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

COX10 Antibody (aa383-410, PE) LS-C221884
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
PE Conjugated
200µl  $680.00

COX10 Antibody (aa383-410, APC) LS-C221878
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

COX10 Antibody (aa383-410, AP) LS-C221877
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

COX10 Antibody (aa383-410, Azide-free, HRP) LS-C221882
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

COX10 Antibody LS-C675574
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human rectal cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human rectal cancer at dilution 1:100

COX10 Antibody LS-C675576
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human rectal cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human rectal cancer at dilution 1:100

COX10 Antibody LS-C412985
Rabbit Polyclonal to Human COX10
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00

COX10 Antibody LS-C403755
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human renal cancer using COX10 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry of Human renal cancer using COX10 Polyclonal Antibody at dilution of 1:100.

COX10 Antibody LS-C349232
Rabbit Polyclonal (IgG) to Human COX10
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines.
Western blot analysis of extracts of various cell lines.

COX10 Antibody LS-C664728
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA WB
Unconjugated
100µg  $335.00

COX10 Antibody (Internal) LS-C382856
Rabbit Polyclonal (IgG) to Human COX10
Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of COX10 antibody
Western blot of COX10 antibody

COX10 Antibody (Internal) LS-C368781
Rabbit Polyclonal to Human COX10
Mouse, Human
IP WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Western blot analysis of COX10 expression in HeLa (A); HEK293T (B); mouse kidney (C); mouse brain (D) whole cell lysates.
Western blot analysis of COX10 expression in HeLa (A); HEK293T (B); mouse kidney (C); mouse brain (D) whole cell lysates.

COX10 Antibody (aa98-147) LS-C199819
Rabbit Polyclonal (IgG) to Human COX10
Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysate from HeLa cells, using COX10 antibody.
Western blot analysis of lysate from HeLa cells, using COX10 antibody.

COX10 Antibody LS-C309968
Rabbit Polyclonal (IgG) to Human COX10
Human
WB
Unconjugated
100µg  $605.00

COX10 Antibody (Biotin) LS-C521443
Rabbit Polyclonal (IgG) to Human COX10
Human
WB
Biotin Conjugated
100µl  $755.00

COX10 Antibody (APC) LS-C513231
Rabbit Polyclonal (IgG) to Human COX10
Human
WB
APC Conjugated
100µl  $755.00

COX10 Antibody (PE) LS-C649690
Rabbit Polyclonal (IgG) to Human COX10
Human
WB
PE Conjugated
100µl  $755.00

COX10 Antibody (AP) LS-C503523
Rabbit Polyclonal (IgG) to Human COX10
Human
WB
AP Conjugated
100µl  $755.00

COX10 Antibody (aa215-264) LS-C111006
Rabbit Polyclonal to Human COX10
Xenopus, Chicken, Zebrafish, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00
COX10 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COX10 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COX10 Antibody (aa180-229) LS-C102158
Rabbit Polyclonal (IgG) to Human COX10
Xenopus, Chicken, Bovine, Rabbit, Mouse, Guinea pig, Rat, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
COX10 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COX10 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COX10 Antibody LS-C307822
Mouse Polyclonal (IgG) to Human COX10
Human
WB
Unconjugated
50µg  $560.00
Showing 1-25 of 33 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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