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CORT / Cortistatin

cortistatin

CORT / Cortistatin is a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.

Gene Name: cortistatin
Synonyms: CORT, Cortistatin-17, Cortistatin-29, Cortistatin-14, CST-14, CST-17, CST-29, Cortistatin, Preprocortistatin
Target Sequences: NM_001302 NP_001293.3

Publications (1)

1
Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. Close JL, Yao Z, Levi BP, Miller JA, Bakken TE, Menon V, Ting JT, Wall A, Krostag AR, Thomsen ER, Nelson AM, Mich JK, Hodge RD, Shehata SI, Glass IA, Bort S, Shapovalova NV, Ngo NK, Grimley JS, Phillips JW, Thompson CL, Ramanathan S, Lein E. Neuron. 2017 March;93:1035-1048. (Human) [Full Text Article] [PubMed:28279351] [PMC:PMC5480972] Related Antibodies: LS-C143717.

☰ Filters
Antibodies (14)
ELISA Kits (8)
Proteins (4)
Competitive EIA (4)
Custom (2)
Over-Expression Lysate (2)
Primary (14)
Recombinant (2)
Sandwich (2)
CORT / Cortistatin (26)
Human (15)
Mouse (2)
Rat (6)
All species (1)
IHC (4)
WB (6)
ELISA (6)
IF (4)
rabbit (14)
IgG (10)
polyclonal pc (14)
96-Well Strip Plate (8)
Biotin Conjugated (2)
FITC Conjugated (1)
HRP Conjugated (1)
Preservative Free (2)
Unconjugated (10)
N-Terminus (4)
No (25)
Yes (1)
Plasma (6)
Serum (6)
Tissue Homogenates (4)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
50 µl/$860
Select
CORT / Cortistatin Rabbit anti-Rat Polyclonal Antibody
Rat, Human
IF, IHC
Unconjugated
50 µl/$860
CORT / Cortistatin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
6.17 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
50 µl/$860
CORT / Cortistatin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Select
CORT / Cortistatin Rabbit anti-Rat Polyclonal Antibody
Rat
IF, IHC
Unconjugated
50 µl/$860
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
400 µg/$856
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
400 µg/$856
CORT / Cortistatin Antibody - CORT / Cortistatin antibody Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CORT / Cortistatin Antibody - CORT / Cortistatin antibody Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
CORT / Cortistatin Antibody - CORT / Cortistatin antibody Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
CORT / Cortistatin Antibody - CORT / Cortistatin antibody Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CORT / Cortistatin Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
Select
CORT / Cortistatin Rabbit anti-Rat Polyclonal Antibody
Rat, Human
ELISA
Unconjugated
400 µg/$856
Select
CORT / Cortistatin Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
400 µg/$856
CORT / Cortistatin ELISA Kit
Select
Custom
96-Well Strip Plate
Human
1 Plate/$783
CORT / Cortistatin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
2.81 - 180 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CORT / Cortistatin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
2.81 - 180 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CORT / Cortistatin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
1 Plate/$783
CORT / Cortistatin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
All species
2.81 - 180 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CORT / Cortistatin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
2.81 - 180 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CORT / Cortistatin Protein - 12.5% SDS-PAGE of human CORT stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.6 kDa
2 µg/$439
CORT / Cortistatin Protein
Select
E. coli
His, N-Terminal
17 kDa
50 µg/$419
CORT / Cortistatin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17 kDa
20 µg/$150
Viewing 1-25 of 26 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).