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COPZ1

coatomer protein complex, subunit zeta 1

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Gene Name: coatomer protein complex, subunit zeta 1
Synonyms: COPZ1, CGI-120, COPZ, HSPC181, Zeta-1-coat protein, Zeta1-COP, Zeta-1 COP, Coatomer subunit zeta-1, Zeta-COP
Target Sequences: NM_016057 NP_057141.1 P61923

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
COPZ1 (5)
No (5)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
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293T Cells
Myc-DDK (Flag)
20 kDa
20 µg/$150
COPZ1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20 kDa
100 µg/$494
COPZ1 Protein - 12.5% SDS-PAGE of human COPZ1 stained with Coomassie Blue
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Wheat Germ Extract
GST
46.6 kDa
10 µg/$479; 25 µg/$670
COPZ1 Protein - Purified recombinant protein COPZ1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
20 kDa
20 µg/$1,107
COPZ1 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).