COPS7A

COP9 signalosome subunit 7A

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

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Products

Antibodies (23)

Proteins (4)

Type

Primary (23)

Recombinant (4)

Target

COPS7A (27)

Reactivity

Human (23)

Mouse (11)

Rat (7)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (4)

Orangutan (3)

Pig (3)

Rabbit (3)

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Application

IHC (15)

IHC-P (7)

WB (22)

ELISA (14)

IP (1)

Peptide-ELISA (1)

Host

rabbit (23)

Isotype

IgG (20)

Clonality

polyclonal pc (23)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (12)

Epitope

aa237-266 (7)

C-Terminus (5)

aa2-275 (4)

aa1-275 (2)

Publications

No (27)

Tag

GST (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (1)

Species

Human (4)

Source

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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COPS7A Antibody (aa1-275) LS-C379790

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa1-275) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

COPS7A Antibody (aa2-275) LS-C372182

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa2-275) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

COPS7A Antibody (aa2-275, HRP) LS-C372177

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa2-275) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

COPS7A Antibody (aa2-275, Biotin) LS-C372181

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa2-275) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

COPS7A Antibody (aa2-275, FITC) LS-C372180

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa2-275) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

COPS7A Antibody LS-C664713

Antibody:

COPS7A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

COPS7A Antibody (aa1-275) LS-C379796

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa1-275) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

COPS7A Antibody (aa237-266) LS-C320524

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

COPS7A Antibody (aa237-266, Biotin) LS-C255262

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

COPS7A Antibody (aa237-266, FITC) LS-C255263

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

COPS7A Antibody (aa237-266, APC) LS-C255261

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

COPS7A Antibody (aa237-266, PE) LS-C255265

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

COPS7A Antibody (aa237-266, Azide-free, HRP) LS-C255264

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

COPS7A Antibody (aa237-266) LS-C166945

Antibody:

COPS7A Rabbit anti-Human Polyclonal (aa237-266) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

COPS7A Antibody LS-C409748

Antibody:

COPS7A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

COPS7A Antibody LS-C781127

Antibody:

COPS7A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

COPS7A Antibody LS-C807169

Antibody:

COPS7A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

COPS7A Antibody LS-C765734

Antibody:

COPS7A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

COPS7A Antibody (C-Terminus) LS-C107924

Antibody:

COPS7A Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

COPS7A Antibody (C-Terminus, HRP) LS-C462612

Antibody:

COPS7A Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

COPS7A Antibody (C-Terminus, Biotin) LS-C462610

Antibody:

COPS7A Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

COPS7A Antibody (C-Terminus, FITC) LS-C462611

Antibody:

COPS7A Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

COPS7A Antibody (C-Terminus) LS-C353424

Antibody:

COPS7A Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Human COPS7A Protein (Recombinant His-SUMO) (Full Length) - LS-G21971

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

46.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human COPS7A Protein (Recombinant GST) (Full Length) - LS-G33552

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

56.7 kDa

Price:

2 µg/$439

Viewing 1-25 of 27 product results

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